Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37737 | 0.91 | PDE5A (0.68) | PDE5AKDM4ELMNAMAPTPOLB | |
| SCHEMBL38235 | 0.82 | PDE5A (0.62) | PDE5AKDM4ELMNAMAPTPOLB | |
| SCHEMBL37798 | 0.81 | PDE5A (1.00) | PDE5AKDM4ELMNAMAPTPOLB | |
| SCHEMBL37513 | 0.80 | PDE5A (0.79) | PDE5AKDM4EKMT2APKMRNASEH1 | |
| SCHEMBL37942 | 0.80 | PDE5A (0.78) | PDE5AKDM4ELMNAPOLBRAB9A | |
| SCHEMBL37583 | 0.78 | PDE5A (0.78) | PDE5AKDM4EKMT2ARNASEH1 | |
| SCHEMBL46310 | 0.77 | PDE5A (0.74) | PDE5AKDM4ELMNAPOLBRAB9A | |
| SCHEMBL38178 | 0.77 | PDE5A (0.77) | PDE5AKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL38065 | 0.77 | PDE5A (0.77) | PDE5ARAB9AKMT2ARNASEH1 | |
| SCHEMBL38116 | 0.76 | PDE5A (0.63) | PDE5AKDM4ELMNAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004900-A1 | THIENOPYRIMIDINE COMPOUNDS | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | WO | disclosed |