Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331649 | 0.87 | KDM4E (0.54) | KDM4ENQO2KMT2AMEN1ATM | |
| SCHEMBL7494307 | 0.84 | MAPT (0.56) | KDM4ENQO2KMT2AMEN1ATM | |
| SCHEMBL25042634 | 0.83 | KDM4E (0.50) | KDM4ENQO2KMT2AMEN1KDR | |
| SCHEMBL9207981 | 0.81 | KDM4E (0.51) | KDM4ENQO2KMT2AMEN1ATM | |
| SCHEMBL15828755 | 0.80 | MEN1 (0.47) | KDM4ENQO2KMT2AMEN1ATM | |
| SCHEMBL3469530 | 0.80 | KDM4E (0.50) | KDM4ENQO2MAPK8ALDH1A1HPGD | |
| SCHEMBL4618392 | 0.79 | KDM4E (0.53) | KDM4ENQO2KMT2AMEN1ATM | |
| SCHEMBL4190262 | 0.79 | ALDH1A1 (0.55) | KDM4EKMT2AMEN1ATML3MBTL1 | |
| SCHEMBL7433737 | 0.76 | HTR3E (0.54) | KDM4EKMT2AMEN1ATML3MBTL1 | |
| SCHEMBL436564 | 0.76 | KDM4E (1.00) | KDM4ENQO2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081562-A1 | DYES FOR NUCLEIC ACID DETECTION | DETECT, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| US-11667961-B2 | Intercalating fluorescent dyes for labelling nucleic acids and preparation method thereof | BIOACTS CORPORATION (KR) | 2023-06-06 | — | — | US | disclosed |
| US-11667961-B2 | Intercalating fluorescent dyes for labelling nucleic acids and preparation method thereof | BIOACTS CORPORATION (KR) | 2023-06-06 | — | — | US | disclosed |
| US-20210198729-A1 | NOVEL INTERCALATING FLUORESCENT DYES FOR LABELLING NUCLEIC ACIDS AND PREPARATION METHOD THEREOF | BIOACTS CORPORATION | 2021-07-01 | — | — | US | disclosed |
| WO-2021105887-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-05-27 | — | — | US | disclosed |
| US-20200263231-A1 | Fluorogenic dyes for high sensitivity DNA detection | Life Technologies Corporation | 2020-08-20 | — | — | US | disclosed |
| EP-2408863-B1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORP (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| EP-0675924-B1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES INC (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5658751-A | SUBSTITUENTS ON PYRIDINIUM OR QUINOLINIUM RING SYSTEM SERVE TO INCREASE OR DECREASE PERMEABILITY, SELECTIVITY AND BINDING AFFINITY OF NUCLEIC ACID STAINS; FORM FLUORESCENT COMPLEXES WITH NUCLEIC ACIDS | MOLECULAR PROBES, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545535-A | USING MIXTURE OF FLUORESCENT DYES | MOLECULAR PROBES, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5534416-A | ANALYZING CELL VIABILITY | MOLECULAR PROBES, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0675924-A1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES, INC. (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5445946-A | Intravacuolar stains for yeast and other fungi | MOLECULAR PROBES, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5436134-A | Fluorescent dyes for nucleic acids | MOLECULAR PROBES, INC. (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1994024213-A1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES, INC. (US) | 1994-10-27 | — | — | WO | disclosed |
| US-4187310-A | ANTIINFLAMMATORY AGENT, ANALGESICS, ENZYME INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-02-05 | — | — | US | disclosed |
| US-4138490-A | Analgesic compositions containing 1,2-dihydro-2-oxoquinol-4-ylpropionic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | ADAR, SSBP1, POLRMT | KDM4E 4308/4885NQO2 2818/4885KMT2A 2023/4885 |
| US-20200263231-A1 | Fluorogenic dyes for high sensitivity DNA detection | POLRMT, POLM, DNMT3A | KDM4E 3509/4885NQO2 73/4885KMT2A 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.