Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 3/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763418 | 0.98 | GAA (0.36) | NPSR1GAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9461267 | 0.71 | PHGDH (0.37) | NPSR1GAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5800001 | 0.68 | NPSR1 (0.44) | NPSR1GAAALDH1A1CYP2C19MEN1 | |
| SCHEMBL9461262 | 0.68 | GAA (0.34) | NPSR1GAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL24920628 | 0.67 | GAA (0.40) | NPSR1GAAALDH1A1ADH1AADH1C | |
| SCHEMBL7296171 | 0.67 | NPSR1 (0.46) | NPSR1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL8186827 | 0.67 | NPSR1 (0.43) | NPSR1GAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5703370 | 0.66 | ADH1A (0.50) | NPSR1GAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10652717 | 0.66 | ADH1A (0.35) | NPSR1GAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23319719 | 0.66 | ADH1A (0.35) | NPSR1GAAALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436166-B2 | Amino-containing vinylsilane compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | BHMT2, GNMT, VASP | NPSR1 2418/4885GAA 4442/4885ALDH1A1 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.