Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789234 | 0.91 | PTGS2 (0.50) | MAOAPTGS2MAP4K4EPHX2MEN1 | |
| SCHEMBL3784048 | 0.87 | MAOA (0.45) | MAOAPTGS2EPHX2MEN1CYP3A4 | |
| SCHEMBL3789813 | 0.86 | MAOA (0.53) | MAOAPTGS2MAP4K4MEN1PSIP1 | |
| SCHEMBL30426786 | 0.83 | CYP3A4 (0.46) | MAOAPTGS2EPHX2MEN1CYP3A4 | |
| SCHEMBL926391 | 0.83 | CYP3A4 (0.46) | MAOAPTGS2EPHX2MEN1CYP3A4 | |
| SCHEMBL3789535 | 0.81 | CYP3A4 (0.42) | MAOAPTGS2EPHX2MEN1CYP3A4 | |
| SCHEMBL3793475 | 0.81 | MAOA (0.52) | MAOAMAP4K4MEN1PSIP1AXL | |
| Hydrochloric Acid SCHEMBL2651523 | 0.81 | CYP3A4 (0.44) | MAOAPTGS2EPHX2MEN1CYP3A4 | |
| SCHEMBL3787437 | 0.79 | PTGS2 (0.56) | MAOAPTGS2EPHX2CYP3A4TP53 | |
| SCHEMBL3785569 | 0.77 | MAOA (0.39) | MAOAPTGS2MAP4K4EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MAOA 348/4885PTGS2 3544/4885MAP4K4 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.