SCHEMBL31045516

SCHEMBL31045516

C#CCCCC#Cc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DPYD Q12882 4/20 0.54
▸ GAA P10253 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ ATAD2 Q6PL18 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CYP19A1 P11511 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ THPO P40225 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ HBB P68871 1/20 0.34
▸ PMP22 Q01453 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295318 0.97 DPYD (0.54) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL1050748 0.83 DPYD (0.47) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL16585678 0.80 GPR84 (0.46) DPYDMAPTALDH1A1ATAD2TSHR
SCHEMBL1890981 0.79 DPYD (0.50) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL887754 0.79 DPYD (0.50) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL17553298 0.75 DPYD (0.46) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL3485393 0.75 DPYD (0.53) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL2001029 0.75 DPYD (0.53) DPYDGAAMAPTALDH1A1ATAD2
SCHEMBL16586721 0.74 GPR84 (0.43) DPYDMAPTLMNATSHRSMN1; SMN2
SCHEMBL16586691 0.74 GPR84 (0.43) DPYDMAPTLMNATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101887-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME ILLUMINA, INC. (US) 2026-05-15 — — WO disclosed
US-20260125412-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME ILLUMINA, INC. (US) 2026-05-07 — — US disclosed
EP-4683927-A1 ALPHA-MODIFIED NUCLEOSIDE TRIPHOSPHATES AND METHOD FOR THEIR SYNTHESIS Illumina, Inc. (US) 2026-01-28 — — EP disclosed
WO-2025230760-A1 REVERSIBLY TERMINATED NUCLEOTIDES WITH MODIFIED PHOSPHATE CHAINS, AND METHODS OF MAKING AND USING THE SAME ILLUMINA, INC. (US) 2025-11-06 — — WO disclosed
WO-2024196883-A1 ALPHA-MODIFIED NUCLEOSIDE TRIPHOSPHATES AND METHOD FOR THEIR SYNTHESIS ILLUMINA, INC. (US) 2024-09-26 — — WO disclosed
US-20240317793-A1 NUCLEOSIDE TRIPHOSPHATES WITH MODIFIED PHOSPHATE CHAINS, AND METHODS OF SYNTHESIZING THE SAME ILLUMINA, INC. (US) 2024-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125412-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME PNP, MTAP, SLC35B2 DPYD 24/4885GAA 1715/4885MAPT 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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