Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045516 | 0.97 | DPYD (0.54) | DPYDGAAMAPTALDH1A1ATAD2 | |
| SCHEMBL16585678 | 0.83 | GPR84 (0.46) | DPYDMAPTALDH1A1ATAD2TSHR | |
| SCHEMBL1050748 | 0.83 | DPYD (0.47) | DPYDGAAMAPTALDH1A1ATAD2 | |
| SCHEMBL1890981 | 0.79 | DPYD (0.50) | DPYDGAAMAPTALDH1A1ATAD2 | |
| SCHEMBL887754 | 0.79 | DPYD (0.50) | DPYDGAAMAPTALDH1A1ATAD2 | |
| SCHEMBL887830 | 0.78 | DPYD (0.58) | DPYDGAAMAPTALDH1A1ATAD2 | |
| SCHEMBL16586721 | 0.76 | GPR84 (0.43) | DPYDMAPTLMNATSHRSMN1; SMN2 | |
| SCHEMBL16586691 | 0.76 | GPR84 (0.43) | DPYDMAPTLMNATSHRSMN1; SMN2 | |
| SCHEMBL17553298 | 0.75 | DPYD (0.46) | DPYDGAAMAPTALDH1A1ATAD2 | |
| SCHEMBL2001029 | 0.75 | DPYD (0.53) | DPYDGAAMAPTALDH1A1ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368655-A1 | CLICK HANDLE-MODIFIED DEOXY-FLUOROARABINO NUCLEIC ACID AS A SYNTHETIC GENETIC POLYMER CAPABLE OF POST-POLYMERIZATION FUNCTIONALIZATION | NATIONAL INSTITUTES OF HEALTH | 2024-11-07 | — | — | US | claimed |
| US-20240368655-A1 | CLICK HANDLE-MODIFIED DEOXY-FLUOROARABINO NUCLEIC ACID AS A SYNTHETIC GENETIC POLYMER CAPABLE OF POST-POLYMERIZATION FUNCTIONALIZATION | NATIONAL INSTITUTES OF HEALTH | 2024-11-07 | — | — | US | disclosed |
| US-20240368655-A1 | CLICK HANDLE-MODIFIED DEOXY-FLUOROARABINO NUCLEIC ACID AS A SYNTHETIC GENETIC POLYMER CAPABLE OF POST-POLYMERIZATION FUNCTIONALIZATION | NATIONAL INSTITUTES OF HEALTH | 2024-11-07 | — | — | US | disclosed |
| EP-4365306-A9 | METHODS FOR DETECTING TARGET POLYNUCLEOTIDES | NunaBio Limited (GB) | 2024-07-03 | — | — | EP | disclosed |
| EP-4365306-A2 | METHODS FOR DETECTING TARGET POLYNUCLEOTIDES | NunaBio Limited (GB) | 2024-05-08 | — | — | EP | disclosed |
| EP-3759253-B1 | METHODS FOR DETECTING TARGET POLYNUCLEOTIDES | NUNABIO LTD (GB) | 2024-03-27 | — | — | EP | disclosed |
| US-20210079449-A1 | METHODS FOR DETECTING TARGET POLYNUCLEOTIDES | NunaBio Limited (GB) | 2021-03-18 | — | — | US | disclosed |
| EP-3759253-A1 | METHODS FOR DETECTING TARGET POLYNUCLEOTIDES | University of Newcastle Upon Tyne (GB) | 2021-01-06 | — | — | EP | disclosed |
| WO-2019162699-A1 | METHODS FOR DETECTING TARGET POLYNUCLEOTIDES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368655-A1 | CLICK HANDLE-MODIFIED DEOXY-FLUOROARABINO NUCLEIC ACID AS A SYNTHETIC GENETIC POLYMER CAPABLE OF POST-POLYMERIZATION FUNCTIONALIZATION | RNGTT, UNG, DCTD | DPYD 64/4885GAA 466/4885MAPT 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.