Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782288 | 0.75 | MAPK1 (0.63) | SLC2A1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20515228 | 0.70 | RXFP1 (0.43) | NCOR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10322427 | 0.70 | RXFP1 (0.55) | NCOR2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL15487148 | 0.69 | DHODH (0.56) | NCOR2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8327229 | 0.68 | KMT2A (0.41) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL8329541 | 0.68 | HDAC1 (0.43) | HDAC1HDAC6HDAC3APPACHE | |
| SCHEMBL4433976 | 0.67 | CSF1R (0.48) | HDAC1HDAC6MAPTKDM4EPHLPP2 | |
| SCHEMBL8328970 | 0.66 | PDE4B (0.40) | HDAC1HDAC6HDAC3APPACHE | |
| SCHEMBL13846125 | 0.65 | EGFR (0.61) | SMN1; SMN2HTTGAA | |
| SCHEMBL18285397 | 0.65 | FABP3 (0.44) | NCOR2MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133672-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXYLIC ACID AND THEIR MEDICAL USE | CLANOTECH AB (SE) | 2010-11-25 | — | — | WO | disclosed |