Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329541 | 0.93 | HDAC1 (0.43) | MAPTKMT2AMEN1GAAPOLB | |
| SCHEMBL8330060 | 0.89 | MAPT (0.39) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL8328444 | 0.88 | MAPT (0.42) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL8324460 | 0.87 | HRH3 (0.41) | MAPTKMT2AKDM4EPOLBRAD52 | |
| SCHEMBL8327229 | 0.86 | KMT2A (0.41) | MAPTKMT2AMEN1GAAPOLB | |
| SCHEMBL8324676 | 0.86 | P2RX3 (0.41) | MAPTKMT2AKDM4EPOLBRAD52 | |
| SCHEMBL8331716 | 0.86 | MAPT (0.37) | MAPTKMT2AMEN1GAAKDM4E | |
| SCHEMBL8326172 | 0.84 | HDAC3 (0.43) | PDE4DKMT2AMEN1GAAPOLB | |
| SCHEMBL8329323 | 0.81 | GAA (0.47) | PDE4BMAPTKMT2AMEN1GAA | |
| SCHEMBL8325775 | 0.76 | MAPT (0.56) | PDE4BMAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |