Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STK4 | Q13043 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629096 | 0.82 | L3MBTL1 (0.39) | EGFRERBB2FABP3FABP4FABP5 | |
| SCHEMBL2912641 | 0.80 | CSF1R (0.60) | CSF1RKDRERBB2EPHA2EPHB4 | |
| SCHEMBL2911203 | 0.77 | CSF1R (0.56) | CSF1REGFRKDRERBB2EPHA2 | |
| SCHEMBL2905929 | 0.76 | CSF1R (0.53) | CSF1RKDRERBB2EPHA2EPHB4 | |
| SCHEMBL2913279 | 0.75 | CSF1R (0.64) | CSF1REGFRSRCMAPT | |
| SCHEMBL4075354 | 0.74 | CSF1R (0.85) | CSF1REGFRERBB2 | |
| SCHEMBL6105688 | 0.72 | EGFR (0.37) | CSF1REGFRKDRKDM4EMAPT | |
| SCHEMBL2908163 | 0.71 | CSF1R (0.64) | CSF1REGFRSRCMAPT | |
| SCHEMBL5929645 | 0.69 | FABP3 (0.47) | CSNK2A1FABP3FABP4FABP5 | |
| SCHEMBL2907522 | 0.68 | CSF1R (0.48) | CSF1REGFRERBB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270450-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270450-A1 | CHEMICAL COMPOUNDS | CSF1R, CSF3R, FLT3 | CSF1R 1/4885EGFR 415/4885SRC 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.