SCHEMBL3782409

SCHEMBL3782409

COc1cc(CBr)ccc1CBr

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.47
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 1/20 0.42
FOS P01100 1/20 0.42
TTR P02766 1/20 0.42
JUN P05412 1/20 0.42
NR3C1 P04150 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30147378 1.00 CA2 (0.47) CA2GAAMAPTTSHRMAPK1
SCHEMBL11842974 0.90 CA2 (0.61) CA2GAAMAPTTSHRMAPK1
SCHEMBL7470025 0.86 KDM4E (0.46) CA2GAAMAPTTSHRMAPK1
SCHEMBL1587262 0.86 PDCD1 (0.47) CA2GAAMAPTTSHRMAPK1
SCHEMBL465122 0.85 GABRA1 (0.46) TSHRMAPK1ALDH1A1KDM4EATM
SCHEMBL10052083 0.83 CA2 (0.47) CA2GAAALDH1A1KDM4EATM
SCHEMBL1080853 0.83 CA2 (0.68) CA2MAPTALDH1A1KDM4EATM
SCHEMBL29559892 0.83 CA2 (0.68) CA2MAPTALDH1A1KDM4EATM
SCHEMBL6228438 0.82 PIK3CD (0.41) CA2GAAMAPTTSHRMAPK1
SCHEMBL11853519 0.81 TSHR (0.48) GAAMAPTTSHRMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714557-B1 METHOD OF PROVIDING A FILM OF CONJUGATED, SUBSTITUTED OR UNSUBSTITUTED POLY(P-PHENYLENE VINYLENE) ON A SUBSTRATE BY CHEMICAL VAPOUR DEPOSITION (CVD), AS WELL AS A METHOD OF MANUFACTURING AN ELECTROLUMINESCENT (EL) DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 1998-11-25 EP claimed
US-5670212-A CVD method of providing a film of conjugated, substituted or unsubstituted poly(p-phenylene vinylene) on a substrate U.S. PHILIPS CORPORATION (US) 1997-09-23 US claimed
US-20230160904-A1 REAGENT FOR MASS SPECTROMETRY ROCHE DIAGNOSTICS OPERATIONS, INC. 2023-05-25 US disclosed
US-20230160904-A1 REAGENT FOR MASS SPECTROMETRY ROCHE DIAGNOSTICS OPERATIONS, INC. 2023-05-25 US disclosed
EP-4154009-A1 REAGENT FOR MASS SPECTROMETRY F. Hoffmann-La Roche AG (CH) 2023-03-29 EP disclosed
WO-2021233997-A1 REAGENT FOR MASS SPECTROMETRY F. HOFFMANN-LA ROCHE AG (CH) 2021-11-25 WO disclosed
EP-2437792-B1 IMAGING OF MYELIN BASIC PROTEIN GEN ELECTRIC (US) 2015-10-21 EP disclosed
US-8617515-B2 Imaging of myelin basic protein GENERAL ELECTRIC COMPANY (US) 2013-12-31 US disclosed
WO-2012054695-A1 NTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE JAMES MADISON INNOVATIONS, INC. (US) 2012-04-26 WO disclosed
US-20100310457-A1 IMAGING OF MYELIN BASIC PROTEIN GENERAL ELECTRIC COMPANY (US) 2010-12-09 US disclosed
US-20100310457-A1 IMAGING OF MYELIN BASIC PROTEIN GENERAL ELECTRIC COMPANY (US) 2010-12-09 US disclosed
US-20100310457-A1 IMAGING OF MYELIN BASIC PROTEIN GENERAL ELECTRIC COMPANY (US) 2010-12-09 US disclosed
EP-0714557-B1 METHOD OF PROVIDING A FILM OF CONJUGATED, SUBSTITUTED OR UNSUBSTITUTED POLY(P-PHENYLENE VINYLENE) ON A SUBSTRATE BY CHEMICAL VAPOUR DEPOSITION (CVD), AS WELL AS A METHOD OF MANUFACTURING AN ELECTROLUMINESCENT (EL) DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 1998-11-25 EP disclosed
US-5670212-A CVD method of providing a film of conjugated, substituted or unsubstituted poly(p-phenylene vinylene) on a substrate U.S. PHILIPS CORPORATION (US) 1997-09-23 US disclosed
EP-0714557-A1 METHOD OF PROVIDING A FILM OF CONJUGATED, SUBSTITUTED OR UNSUBSTITUTED POLY(P-PHENYLENE VINYLENE) ON A SUBSTRATE BY CHEMICAL VAPOUR DEPOSITION (CVD), AS WELL AS A METHOD OF MANUFACTURING AN ELECTROLUMINESCENT (EL) DEVICE Koninklijke Philips Electronics N.V. (NL) 1996-06-05 EP disclosed
WO-1995031831-A1 METHOD OF PROVIDING A FILM OF CONJUGATED, SUBSTITUTED OR UNSUBSTITUTED POLY(P-PHENYLENE VINYLENE) ON A SUBSTRATE BY CHEMICAL VAPOUR DEPOSITION (CVD), AS WELL AS A METHOD OF MANUFACTURING AN ELECTROLUMINESCENT (EL) DEVICE PHILIPS ELECTRONICS N.V. (NL) 1995-11-23 WO disclosed
US-5312913-A Complexes of electron donors and electron acceptors IDEMITSU KOSAN CO., LTD. (JP) 1994-05-17 US disclosed
US-5175280-A Electroconductive complexes; heat resistance IDEMITSU KOSAN CO., LTD. (JP) 1992-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100310457-A1 IMAGING OF MYELIN BASIC PROTEIN MAG, PMP22, MYT1 CA2 3576/4885GAA 3352/4885MAPT 1129/4885
US-20230160904-A1 REAGENT FOR MASS SPECTROMETRY SRMS, AKR7A2, PTMS CA2 1051/4885GAA 533/4885MAPT 3634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.