SCHEMBL1080853

SCHEMBL1080853

COc1ccc(CBr)cc1OC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.68
ATM Q13315 2/20 0.59
KDM4E B2RXH2 1/20 0.59
ALDH1A1 P00352 2/20 0.57
PPARG P37231 1/20 0.57
PPARD Q03181 1/20 0.57
PPARA Q07869 1/20 0.57
POLB P06746 2/20 0.55
CYP19A1 P11511 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
BLM P54132 1/20 0.53
PMP22 Q01453 1/20 0.53
AOC3 Q16853 1/20 0.52
LDHA P00338 1/20 0.52
CA1 P00915 2/20 0.51
CA9 Q16790 2/20 0.51
CA12 O43570 1/20 0.51
SIGMAR1 Q99720 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559892 1.00 CA2 (0.68) CA2ATMKDM4EALDH1A1PPARG
SCHEMBL9706259 0.86 CA2 (0.52) CA2ATMKDM4EPPARACYP1A2
SCHEMBL9705574 0.86 CA2 (0.52) CA2ATMKDM4EALDH1A1PPARG
SCHEMBL9937910 0.84 CA2 (0.48) CA2ATMKDM4EALDH1A1PPARG
SCHEMBL6794956 0.83 CA2 (0.48) CA2KDM4ESIGMAR1
SCHEMBL6358873 0.83 CA2 (0.48) CA2ATMKDM4EALDH1A1PPARG
SCHEMBL6801155 0.83 SIGMAR1 (0.51) CA2SIGMAR1
SCHEMBL6353922 0.83 CA2 (0.48) CA2ATMKDM4EALDH1A1PPARG
SCHEMBL516206 0.83 ATM (0.66) CA2ATMKDM4EALDH1A1PPARG
SCHEMBL30764700 0.83 ATM (0.66) CA2ATMKDM4EALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843579-A Benzo heterocycle coupled catechol derivative and preparation method and application thereof 暨南大学 2024-04-09 CN claimed
CN-117025063-B Preparation method of metal corrosion inhibition anticorrosive paint 山东国智新材料科技有限公司 2023-12-12 CN claimed
CN-117025063-A Preparation method of metal corrosion inhibition anticorrosive paint 山东国智新材料科技有限公司 2023-11-10 CN claimed
CN-112538025-A Preparation method of fluorine-containing compound for hydrophobic surface treatment agent 湖北福力德鞋业有限责任公司 2021-03-23 CN claimed
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins AVILAR THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-12534436-B2 Disubstituted adamantyl derivative or pharmaceutically acceptable salt thereof, and pharmaceutical composition for suppressing cancer growth comprising same as active ingredient ONECUREGEN CO., LTD. (KR) 2026-01-27 US disclosed
EP-4638438-A1 ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF Xinthera, Inc. (US) 2025-10-29 EP disclosed
US-20250214955-A1 IMPROVED SYNTHETIC METHODS FOR MAKING LACTONES P2 SCIENCE, INC. 2025-07-03 US disclosed
CN-119977833-A Synthesis and antitumor application of erianin derivative 江苏海洋大学 2025-05-13 CN disclosed
CN-119859146-A Gamma-lactam podophyllotoxin compound and preparation method and application thereof 河南农业大学 2025-04-22 CN disclosed
CN-118388348-B Steviol derivative and preparation method and application thereof 广东工业大学 2024-12-27 CN disclosed
US-12162902-B2 Decarboxylase inhibitors for treating Parkinson's disease SAIL BIOMEDICINES (US) 2024-12-10 US disclosed
EP-0031253-B1 PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP disclosed
EP-0073645-A2 2-Cyclic amino-2-(1,2-benzisoxazol-3-yl)acetic acid ester derivatives, process for the preparation thereof and composition containing the same Dainippon Pharmaceutical Co., Ltd. (JP) 1983-03-09 EP disclosed
US-4335263-A MANY STEPS, STARTING WITH ACETYLATION OF M-CRESOL OR P-CRESOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-15 US disclosed
EP-0034894-A2 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives, processes for their preparation, intermediates used in the processes and the preparation thereof and pharmaceutical compositions containing the derivatives AYERST, MCKENNA AND HARRISON INC. (CA) 1981-09-02 EP disclosed
US-4280008-A CHEMICAL INTERMEDIATES FOR OPTICALLY ACTIVE AMINO ACIDS BASF AKTIENGESELLSCHAFT (DE) 1981-07-21 US disclosed
EP-0031253-A1 Process for preparing 3,4-substituted benzaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-01 EP disclosed
US-4166062-A HYPOTENSIVE AGENTS, CNS, ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1979-08-28 US disclosed
US-3962281-A METHOD OF PREPARING ALDEHYDES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214955-A1 IMPROVED SYNTHETIC METHODS FOR MAKING LACTONES LSS, FDPS, NISCH CA2 3677/4885ATM 3914/4885KDM4E 2200/4885
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins IGF2R, M6PR, MSR1 CA2 2683/4885ATM 3428/4885KDM4E 3769/4885
US-12162902-B2 Decarboxylase inhibitors for treating Parkinson's disease DDC, DDT, DDO CA2 2384/4885ATM 2487/4885KDM4E 2529/4885
US-12534436-B2 Disubstituted adamantyl derivative or pharmaceutically acceptable salt thereof, and pharmaceutical composition for suppressing cancer growth comprising same as active ingredient CS, AK2, TFAM CA2 435/4885ATM 1591/4885KDM4E 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.