Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787924 | 0.83 | HPGD (0.62) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL3790237 | 0.80 | NPC1 (0.56) | SMN1; SMN2ALDH1A1MAOBLMNAMAPT | |
| SCHEMBL3784903 | 0.79 | RAB9A (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL3784938 | 0.78 | HPGD (0.44) | CYP1A2CYP2C9CYP2C19HPGDKCNQ4 | |
| SCHEMBL3787132 | 0.78 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL3789898 | 0.77 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL3786631 | 0.77 | MAPK1 (0.62) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL3790236 | 0.76 | MAPT (0.47) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL28401182 | 0.76 | ALDH1A1 (0.72) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL3784763 | 0.76 | KDM4E (0.57) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP1A2 170/4885CYP2C9 157/4885CYP2C19 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.