SCHEMBL3783584

SCHEMBL3783584

CCNc1cccc(N)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.40
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 3/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
GFER P55789 1/20 0.39
PLEC Q15149 1/20 0.39
USP2 O75604 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CASP1 P29466 1/20 0.38
BRCA1 P38398 1/20 0.38
CASP7 P55210 1/20 0.38
IDO1 P14902 1/20 0.35
LMNA P02545 3/20 0.35
TSHR P16473 3/20 0.34
CYP3A4 P08684 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3785895 0.85 FABP4 (0.45) FABP4MAPTALDH1A1HTTUSP2
SCHEMBL3088415 0.79 MEN1 (0.50) FABP4MAPTGAAUSP2MEN1
SCHEMBL6118035 0.79 CD44 (0.43) MAPTALDH1A1GAAHTTKDM4E
SCHEMBL650708 0.79 MAPT (0.47) MAPTALDH1A1GAAHTTKDM4E
SCHEMBL29922726 0.79 MAPT (0.47) MAPTALDH1A1GAAHTTKDM4E
SCHEMBL8898753 0.78 CYP3A4 (0.52) MAPTALDH1A1GAAHTTKDM4E
Hydrochloric Acid SCHEMBL3395899 0.78 MEN1 (0.48) FABP4MAPTALDH1A1GAAUSP2
SCHEMBL30688925 0.77 KDM4E (0.40) MAPTALDH1A1GAAKDM4EHPGD
SCHEMBL3786406 0.77 ALDH1A1 (0.41) FABP4MAPTALDH1A1GAAKDM4E
Ammonia Solution, Strong SCHEMBL3076461 0.77 MAPT (0.46) MAPTALDH1A1GAAHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 FABP4 3879/4885MAPT 3312/4885ALDH1A1 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.