Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23246104 | 0.81 | P2RX7 (0.42) | P2RX7EPHX2NR1H4GAAHSD11B1 | |
| SCHEMBL19149260 | 0.80 | FAAH (0.41) | P2RX7EPHX2LMNA | |
| SCHEMBL6085545 | 0.75 | POLB (0.41) | P2RX7 | |
| SCHEMBL3798119 | 0.71 | DGAT1 (0.51) | — | |
| SCHEMBL19148915 | 0.69 | EPHX1 (0.41) | P2RX7EPHX2HSD11B1LMNA | |
| SCHEMBL59961 | 0.67 | CYP2C9 (0.36) | P2RX7EPHX2GAAHSD11B1 | |
| SCHEMBL1088728 | 0.66 | THRB (0.35) | EPHX2GAAHSD11B1 | |
| SCHEMBL3179851 | 0.65 | KMT2A (0.35) | EPHX2HSD11B1LMNA | |
| SCHEMBL11428920 | 0.65 | — | — | |
| SCHEMBL28231046 | 0.65 | ESR1 (0.42) | GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010095041-A2 | COMPOSITIONS, METHODS, AND KITS FOR TREATING INFLUENZA VIRAL INFECTIONS | EXCRX (SINGAPORE) PTE.LTD. (SG) | 2010-08-26 | — | — | WO | disclosed |