SCHEMBL3784511

SCHEMBL3784511

CCNc1nc(Cl)nc(C(C)CN)n1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
KMT2A Q03164 3/20 0.41
MAPT P10636 1/20 0.41
GAA P10253 5/20 0.41
PDE4A P27815 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9807514 0.82 LMNA (0.67) LMNAKMT2AMAPTGAAPDE4A
SCHEMBL11311696 0.80 ALDH1A1 (0.38) GAATDP1
SCHEMBL11785782 0.80 LMNA (0.53) LMNAKMT2AMAPTGAAPDE4A
Simazine SCHEMBL37774 0.75 LMNA (1.00) LMNAKMT2AMAPTGAAPDE4A
SCHEMBL4831154 0.75 LMNA (0.90) LMNAKMT2AMAPTGAAPDE4A
Simazine SCHEMBL8409822 0.75 LMNA (1.00) LMNAKMT2AMAPTGAAPDE4A
Simazine SCHEMBL9130727 0.75 LMNA (1.00) LMNAKMT2AMAPTGAAPDE4A
SCHEMBL2790765 0.74 ALDH1A1 (0.31) GAATDP1
SCHEMBL8321320 0.74 LMNA (0.50) LMNAKMT2AMAPTGAAPDE4A
Simazine SCHEMBL28076157 0.73 LMNA (0.95) LMNAKMT2AMAPTGAAPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001775-A 2-CHLORO-4-ETHYLAMINO-6-ISOPROPYLAMINE-S-TRIAZINE, A NITROGEN CONTAINING COMPONENT, A PHOSPHORUS CONTAINING COMPONENT, POTASSIUM SULFATE; STRUCTURED TO DISINTEGRATE AND RELEASE INTO A STREAM OF FLOWING WATER KERRIGAN KURT J (US) 1999-12-14 US claimed
CN-114621780-A Preparation method and application of corn straw biochar 昆明理工大学 2022-06-14 CN disclosed
WO-2019218027-A1 CORE-SHELL PARTICLES MONASH UNIVERSITY (AU) 2019-11-21 WO disclosed
US-8222187-B2 Method for improving the phytoremediation of polluted sites by providing plants with exogenous carbohydrates UNIVERSITE DE RENNES 1 (FR) 2012-07-17 US disclosed
US-20100323890-A1 METHOD FOR IMPROVING THE RESISTANCE OF PLANTS TO STRESS AND CORRESPONDING PRODUCTS CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE) (FR) 2010-12-23 US disclosed
US-20070093388-A1 Method for improving the phytoremediation of polluted sites by providing plants with exogenous carbohydrates UNIVERSITE DE RENNES 1 (FR) 2007-04-26 US disclosed
EP-1051070-A1 WATER-DISPERSIBLE FLAKE COMPOSITIONS ZENECA LIMITED (GB) 2000-11-15 EP disclosed
US-6001775-A 2-CHLORO-4-ETHYLAMINO-6-ISOPROPYLAMINE-S-TRIAZINE, A NITROGEN CONTAINING COMPONENT, A PHOSPHORUS CONTAINING COMPONENT, POTASSIUM SULFATE; STRUCTURED TO DISINTEGRATE AND RELEASE INTO A STREAM OF FLOWING WATER KERRIGAN KURT J (US) 1999-12-14 US disclosed
WO-1999039577-A1 WATER-DISPERSIBLE FLAKE COMPOSITIONS ZENECA LIMITED (GB) 1999-08-12 WO disclosed
US-5851777-A Homogeneous sol-sol assay DADE BEHRING INC. (US) 1998-12-22 US disclosed
EP-0819253-A1 HOMOGENEOUS SOL-SOL ASSAY DADE BEHRING INC. (US) 1998-01-21 EP disclosed
WO-1997028451-A1 HOMOGENEOUS SOL-SOL ASSAY DADE INTERNATIONAL INC. (US) 1997-08-07 WO disclosed
EP-0252897-B1 Formulations of water-dispersible granules and process for preparation thereof MONSANTO CO (US) 1994-02-16 EP disclosed
US-4936901-A Formulations of water-dispersible granules and process for preparation thereof MONSANTO COMPANY (US) 1990-06-26 US disclosed
US-4657581-A AMIDE COMPOUNDS, OF DI OR TETRAHYDRO-1 NAPHTHOIC ACID SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-14 US disclosed
US-4224444-A STEP-WISE REPLACEMENT OF TWO CHLORINE ATOMS FROM CYANURIC CHLORIDE RUMIANCA S.P.A. (IT) 1980-09-23 US disclosed
US-3948636-A NONIONIC SURFACTANT, HETEROPOLYSACCHARIDE GUM DIAMOND SHAMROCK CORPORATION (US) 1976-04-06 US disclosed