SCHEMBL2790765

SCHEMBL2790765

CC(N)c1nc(Cl)nc(C(C)CN)n1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11311696 0.89 ALDH1A1 (0.38) ALDH1A1TAAR1GAATDP1
SCHEMBL6449607 0.84 ALDH1A1 (0.39) ALDH1A1GAATDP1
SCHEMBL28422033 0.82 ALDH1A1 (0.44) ALDH1A1GAATDP1
SCHEMBL6451746 0.76
SCHEMBL3784511 0.74 LMNA (0.58) GAATDP1
SCHEMBL28118989 0.72 SLC6A2 (0.34)
SCHEMBL1318974 0.69 ALDH1A1 (0.40) ALDH1A1GAATDP1
SCHEMBL7736920 0.68 GAA (0.67) ALDH1A1GAATDP1
SCHEMBL9491734 0.67 TAAR1 (0.31) TAAR1
SCHEMBL27651462 0.66 SMN1; SMN2 (0.62) ALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200107547-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use ARYSTA LIFESCIENCE CORP (JP) 2020-04-09 US claimed
WO-2010143071-A2 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2010-12-16 WO claimed
US-20100311589-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2010-12-09 US claimed
US-7699979-B2 Separation system and efficient capture of contaminants using magnetic nanoparticles BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2010-04-20 US claimed
US-20080135490-A1 Immunomagnetically separating the contaminant, quantum dot-immunolabeling the contaminant, and detecting and analyzing a characteristic emission spectrum of the quantum dot BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2008-06-12 US claimed
US-20070114181-A1 Separation system and efficient capture of contaminants using magnetic nanoparticles BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2007-05-24 US claimed
US-11917994-B2 Carbamoyl triazolinone based herbicide combinations and method of use ARYSTA LIFESCIENCE CORPORATION (JP) 2024-03-05 US disclosed
US-11432549-B2 Carbamoyl triazolinone based herbicide combinations and method of use ARYSTA LIFESCIENCE CORPORATION (JP) 2022-09-06 US disclosed
CN-108064160-B A pharmaceutical composition containing extract or fraction of mixture of peony root bark, dahurian angelica root and bupleurum root as active ingredient 庆熙大学校产学协力团 2021-05-11 CN disclosed
US-10660928-B2 Pharmaceutical composition containing combination extracts of Moutan Root Bark, Angelica Dahurica Root, bupleurum root or fractions thereof for prevention and treatment of neurodegenerative disorder UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2020-05-26 US disclosed
CN-111109270-A Herbicidal compositions based on carbamoyltriazolinone and methods of use 爱利思达生命科学公司 2020-05-08 CN disclosed
US-20200107547-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use ARYSTA LIFESCIENCE CORP (JP) 2020-04-09 US disclosed
US-20190223439-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use ARYSTA LIFESCIENCE CORPORATION (JP) 2019-07-25 US disclosed
EP-3199171-A1 PHARMACEUTICAL COMPOSITION FOR TREATING AND PREVENTING DEGENERATIVE NEUROLOGICAL DISORDERS, CONTAINING, AS ACTIVE INGREDIENT, MIXTURE EXTRACT OF MOUTAN ROOT BARK, ANGELICA DAHURICA ROOT AND BUPLEURUM ROOT OR FRACTION THEREOF University-Industry Cooperation Group of Kyung Hee University (KR) 2017-08-02 EP disclosed
US-20140051579-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2014-02-20 US disclosed
WO-2010143071-A2 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2010-12-16 WO disclosed
US-20100311589-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2010-12-09 US disclosed
US-20080135490-A1 Immunomagnetically separating the contaminant, quantum dot-immunolabeling the contaminant, and detecting and analyzing a characteristic emission spectrum of the quantum dot BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2008-06-12 US disclosed
US-20050054531-A1 N-(phosphonomethyl) glycine (glyphosate) salt, a preparation process thereof, a concentrate composition and a phytotoxic formulation comprising it, and a method to combat weeds in a crop with a formulation thereto REPOSO S.A.I.C. (AR) 2005-03-10 US disclosed
US-4382865-A Treatment of reducible halohydrocarbon containing aqueous stream ENVIROGENICS SYSTEMS COMPANY (US) 1983-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917994-B2 Carbamoyl triazolinone based herbicide combinations and method of use DDT, NOTUM, WEE1 ALDH1A1 1478/4885TAAR1 2177/4885GAA 1049/4885
US-10660928-B2 Pharmaceutical composition containing combination extracts of Moutan Root Bark, Angelica Dahurica Root, bupleurum root or fractions thereof for prevention and treatment of neurodegenerative disorder HSPA5, PARK7, HSPA9 ALDH1A1 1670/4885TAAR1 3734/4885GAA 1386/4885
US-20190223439-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use DDT, NOTUM, WEE1 ALDH1A1 1478/4885TAAR1 2177/4885GAA 1049/4885
US-20200107547-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use DDT, NOTUM, WEE1 ALDH1A1 1478/4885TAAR1 2177/4885GAA 1049/4885
US-20140051579-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE DDT, NOTUM, WEE1 ALDH1A1 1367/4885TAAR1 2009/4885GAA 1043/4885
US-11432549-B2 Carbamoyl triazolinone based herbicide combinations and method of use DDT, NOTUM, WEE1 ALDH1A1 1478/4885TAAR1 2177/4885GAA 1049/4885
US-20050054531-A1 N-(phosphonomethyl) glycine (glyphosate) salt, a preparation process thereof, a concentrate composition and a phytotoxic formulation comprising it, and a method to combat weeds in a crop with a formulation thereto PHOSPHO1, GNMT, AGL ALDH1A1 3960/4885TAAR1 3135/4885GAA 626/4885
US-20100311589-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE DDT, NOTUM, WEE1 ALDH1A1 1478/4885TAAR1 2177/4885GAA 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.