Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclooctane SCHEMBL9815451 | 1.00 | CA1 (0.33) | CA1CA2CA9TSHRALDH1A1 | |
| Cyclohexane SCHEMBL10358872 | 1.00 | CA1 (0.33) | CA1CA2CA9TSHRALDH1A1 | |
| Cyclopentane SCHEMBL525206 | 1.00 | CA1 (0.33) | CA1CA2CA9TSHRALDH1A1 | |
| Bicarbonate SCHEMBL9492587 | 0.86 | CA1 (0.39) | CA1CA2CA9 | |
| Bicarbonate SCHEMBL9005152 | 0.86 | CA1 (0.39) | CA1CA2CA9 | |
| Cyclohexane SCHEMBL4940109 | 0.86 | TRIM24 (0.38) | TSHRALDH1A1TRIM24TRIM33 | |
| Tetrahydrofuran SCHEMBL4424029 | 0.83 | ALDH1A1 (0.42) | ALDH1A1 | |
| Benzene SCHEMBL626626 | 0.83 | CA9 (0.36) | CA1CA2CA9TSHRALDH1A1 | |
| Bicarbonate SCHEMBL18685960 | 0.83 | CA1 (0.36) | CA1CA2CA9 | |
| Bicarbonate SCHEMBL5695776 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466680-B1 | PLASTIC LAMINATE FILM | LG CHEMICAL LTD (KR) | 2021-02-17 | — | — | EP | claimed |
| EP-2766920-B1 | SPIN-ON CARBON COMPOSITIONS FOR LITHOGRAPHIC PROCESSING | BREWER SCIENCE INC (US) | 2020-12-02 | — | — | EP | claimed |
| EP-3101049-B1 | POLYIMIDE AND FILM USING SAME | KOLON INC (KR) | 2020-11-11 | — | — | EP | claimed |
| EP-3402852-B1 | CARBOXYFUNCTIONAL POLYETHER BASED REACTION PRODUCTS AND AQUEOUS BASE PAINTS CONTAINING THE REACTION PRODUCTS | BASF COATINGS GMBH (DE) | 2019-12-18 | — | — | EP | claimed |
| EP-2861650-B1 | POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM | KOLON INC (KR) | 2019-03-20 | — | — | EP | claimed |
| EP-3088440-B1 | TRANSPARENT POLYAMIDE-IMIDE RESIN AND FILM USING SAME | KOLON INC (KR) | 2018-09-19 | — | — | EP | claimed |
| EP-2867276-B1 | POLYIMIDE AND POLYIMIDE FILM COMPRISING THE SAME | KOLON INC (KR) | 2018-04-18 | — | — | EP | claimed |
| EP-2787024-B1 | Thermosetting composition, hardened film and electronic component | JNC CORP (JP) | 2017-04-05 | — | — | EP | claimed |
| EP-2178952-B1 | POLYIMIDE FILM WITH IMPROVED THERMAL STABILITY | KOLON INC (KR) | 2016-03-16 | — | — | EP | claimed |
| EP-1199604-B1 | METHOD FOR FORMING POLYIMIDE PATTERN USING PHOTOSENSITIVE POLYIMIDE AND COMPOSITION FOR USE THEREIN | PI R & D CO LTD (JP) | 2014-05-21 | — | — | EP | claimed |
| EP-1674570-B1 | Method of isolating nucleic acid using material positively charged at first pH and containing amino group and carboxyl group | SAMSUNG ELECTRONICS CO LTD (KR) | 2010-12-01 | — | — | EP | claimed |
| EP-0768559-B1 | Active-matrix liquid crystal displays with polyimide alignment films from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines | DU PONT (US) | 2003-08-13 | — | — | EP | claimed |
| EP-1064319-B1 | POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORP (JP) | 2003-02-19 | — | — | EP | claimed |
| EP-0575986-B1 | Agent for vertical orientation treatment of liquid crystal molecules | NISSAN CHEMICAL IND LTD (JP) | 1999-11-03 | — | — | EP | claimed |
| EP-0368204-B2 | Ferroelectric liquid crystal element | NISSAN CHEMICAL IND LTD (JP) | 1998-08-26 | — | — | EP | claimed |
| EP-0249881-B1 | LIQUID CRYSTAL ALIGNING AGENT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-10-03 | — | — | EP | claimed |
| EP-3402852-B1 | CARBOXYFUNCTIONAL POLYETHER BASED REACTION PRODUCTS AND AQUEOUS BASE PAINTS CONTAINING THE REACTION PRODUCTS | BASF COATINGS GMBH (DE) | 2019-12-18 | — | — | EP | disclosed |