Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclooctane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3784747 | 1.00 | CA1 (0.33) | CA1CA2CA9TSHRALDH1A1 | |
| Cyclohexane SCHEMBL10358872 | 1.00 | CA1 (0.33) | CA1CA2CA9TSHRALDH1A1 | |
| Cyclopentane SCHEMBL525206 | 1.00 | CA1 (0.33) | CA1CA2CA9TSHRALDH1A1 | |
| Bicarbonate SCHEMBL9492587 | 0.86 | CA1 (0.39) | CA1CA2CA9 | |
| Bicarbonate SCHEMBL9005152 | 0.86 | CA1 (0.39) | CA1CA2CA9 | |
| Cyclohexane SCHEMBL4940109 | 0.86 | TRIM24 (0.38) | TSHRALDH1A1TRIM24TRIM33 | |
| Tetrahydrofuran SCHEMBL4424029 | 0.83 | ALDH1A1 (0.42) | ALDH1A1 | |
| Benzene SCHEMBL626626 | 0.83 | CA9 (0.36) | CA1CA2CA9TSHRALDH1A1 | |
| Bicarbonate SCHEMBL18685960 | 0.83 | CA1 (0.36) | CA1CA2CA9 | |
| Bicarbonate SCHEMBL5695776 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141781-B1 | LIGHT-SENSITIVE COATING COMPOSITION AND USE THEREOF | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| EP-0134752-B1 | LAYERED MATERIAL AND ITS USE | CIBA-GEIGY AG (CH) | 1988-01-27 | — | — | EP | disclosed |
| EP-0141781-A2 | Light-sensitive coating composition and use thereof | CIBA-GEIGY AG (CH) | 1985-05-15 | — | — | EP | disclosed |
| EP-0134752-A1 | Layered material and its use | CIBA-GEIGY AG (CH) | 1985-03-20 | — | — | EP | disclosed |