Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.50 |
| ▸ | S100A10 | P60903 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603037 | 0.88 | MAOA (0.47) | CYP3A4HSD17B10MAOAANXA2S100A10 | |
| SCHEMBL16361082 | 0.88 | MAOA (0.47) | CYP3A4HSD17B10MAOAANXA2S100A10 | |
| SCHEMBL29540354 | 0.88 | HTR2C (0.48) | HSD17B10MAOAHTR2CHTR6ALDH1A1 | |
| SCHEMBL28741318 | 0.88 | HTR2C (0.48) | HSD17B10MAOAHTR2CHTR6ALDH1A1 | |
| SCHEMBL3791331 | 0.86 | MAOA (0.65) | CYP3A4MAOAANXA2S100A10HTR2C | |
| SCHEMBL4985310 | 0.86 | CYP3A4 (0.71) | CYP3A4HSD17B10TAAR1TDP1MAOA | |
| SCHEMBL3784907 | 0.86 | CYP3A4 (0.67) | CYP3A4HSD17B10TAAR1TDP1MAOA | |
| SCHEMBL16361079 | 0.85 | MAOA (0.48) | CYP3A4HSD17B10MAOAHTR2CHTR6 | |
| SCHEMBL3792894 | 0.85 | MAOA (0.69) | CYP3A4HSD17B10TAAR1TDP1MAOA | |
| SCHEMBL3787203 | 0.83 | CYP3A4 (0.50) | CYP3A4HSD17B10TAAR1TDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP3A4 177/4885HSD17B10 1100/4885TAAR1 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.