SCHEMBL3786382

SCHEMBL3786382

CC(C)(C)C(=O)Nc1cc(Cl)cc(NC(=O)C(C)(C)C)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
GAA P10253 1/20 0.53
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
NPSR1 Q6W5P4 2/20 0.49
MAPT P10636 4/20 0.47
HTT P42858 2/20 0.47
ALDH1A1 P00352 1/20 0.47
RAB9A P51151 3/20 0.46
LMNA P02545 1/20 0.46
NPC1 O15118 1/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
LCK P06239 1/20 0.44
CTSL P07711 1/20 0.44
PTPRC P08575 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14254938 0.96 L3MBTL1 (0.59) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL23441 0.89 L3MBTL1 (0.73) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL3867385 0.87 L3MBTL1 (0.50) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL11557777 0.82 MEN1 (0.47) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL5047364 0.81 NPSR1 (0.65) L3MBTL1MEN1KMT2ANPSR1MAPT
SCHEMBL15723377 0.81 L3MBTL1 (0.61) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL2587336 0.80 S1PR2 (0.62) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL9402610 0.80 GAA (0.59) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL28883 0.79 L3MBTL1 (0.79) L3MBTL1GAAMEN1KMT2AMAPT
SCHEMBL7080547 0.79 L3MBTL1 (0.53) L3MBTL1GAAMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 L3MBTL1 3838/4885GAA 1755/4885MEN1 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.