SCHEMBL3786517

SCHEMBL3786517

NC(=O)c1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.65
MKNK1 Q9BUB5 7/20 0.59
MKNK2 Q9HBH9 7/20 0.59
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
ALDH1A1 P00352 2/20 0.55
CYP3A4 P08684 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
TP53 P04637 1/20 0.55
KMT2A Q03164 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
POLB P06746 1/20 0.50
PARP1 P09874 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL9460959 1.00 PARP10 (0.65) PARP10MKNK1MKNK2CA12CA1
Terephthalamide SCHEMBL437011 0.92 PARP10 (0.74) PARP10MKNK1MKNK2CA1CA2
SCHEMBL56532 0.92 PARP10 (0.74) PARP10MKNK1MKNK2CA1CA2
SCHEMBL7642130 0.92 PARP10 (0.74) PARP10MKNK1MKNK2CA1CA2
Water SCHEMBL6343332 0.90 PARP10 (0.71) PARP10MKNK1MKNK2CA1CA2
Hydrochloric Acid SCHEMBL4408462 0.90 PARP10 (0.71) PARP10MKNK1MKNK2CA1CA2
SCHEMBL1002578 0.89 CA2 (0.67) PARP10MKNK1MKNK2CA12CA1
Biphenyl SCHEMBL28602112 0.89 CYP3A4 (0.62) PARP10MKNK1MKNK2CYP3A4TDP1
SCHEMBL28503217 0.88 PARP10 (0.89) PARP10MKNK1MKNK2CA1CA2
Benzene SCHEMBL6865184 0.87 PARP10 (0.68) PARP10MKNK1MKNK2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104691066-B Low dielectric constant multilayer polyimide film, laminate thereof, and method for producing same 达迈科技股份有限公司 2018-07-03 CN claimed
CN-104691066-A Low dielectric constant multilayer polyimide film, laminate thereof, and method for producing same TAIMIDE TECHNOLOGY INC 2015-06-10 CN claimed
CN-104691066-B Low dielectric constant multilayer polyimide film, laminate thereof, and method for producing same 达迈科技股份有限公司 2018-07-03 CN disclosed
CN-104822524-B Copper foil with carrier JX日矿日石金属株式会社 2016-09-28 CN disclosed
CN-104822524-A Carrier-supported copper foil JX NIPPON MINING &AMP 2015-08-05 CN disclosed
CN-104822525-A Copper foil with carrier JX NIPPON MINING & METALS CORP 2015-08-05 CN disclosed
CN-104812944-A Copper foil with carrier JX NIPPON MINING & METALS CORP 2015-07-29 CN disclosed
CN-104691066-A Low dielectric constant multilayer polyimide film, laminate thereof, and method for producing same TAIMIDE TECHNOLOGY INC 2015-06-10 CN disclosed
CN-104619889-A Copper foil with carrier JX NIPPON MINING & METALS CORP 2015-05-13 CN disclosed
CN-104584699-A Copper foil with carrier JX NIPPON MINING & METALS CORP 2015-04-29 CN disclosed
CN-102585844-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element containing same CHI MEI CORP 2014-03-12 CN disclosed
CN-102585844-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element containing same CHI MEI CORP 2012-07-18 CN disclosed
CN-101576687-B Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHI MEI IND CO LTD 2011-07-20 CN disclosed
CN-102051185-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element CHI MEI IND CO LTD 2011-05-11 CN disclosed
CN-101614912-B Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP 2011-01-05 CN disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
CN-101614912-A Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP 2009-12-30 CN disclosed
CN-101576687-A Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP (CN) 2009-11-11 CN disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
US-20050065195-A1 Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors GLAXO GROUP LIMITED (GB) 2005-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065195-A1 Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors MAPK3, MAPK1, MAPKAPK3 PARP10 3641/4885MKNK1 175/4885MKNK2 157/4885
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 PARP10 1861/4885MKNK1 3527/4885MKNK2 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.