Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512824 | 0.77 | CDK8 (0.41) | MAPTSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL510530 | 0.73 | MAPK8 (0.36) | KMT2AMAPTSMN1; SMN2HTTCYP3A4 | |
| SCHEMBL469902 | 0.72 | CRHR1 (0.34) | CRHR1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL1517425 | 0.70 | NR2F2 (0.34) | MAPT | |
| SCHEMBL919414 | 0.70 | KMT2A (0.37) | FPR2PROKR1MEN1KMT2AMAPT | |
| SCHEMBL12481433 | 0.69 | KDM4E (0.33) | SMN1; SMN2FPR1ALDH1A1KDM4E | |
| SCHEMBL514400 | 0.68 | MMP1 (0.31) | SMN1; SMN2 | |
| SCHEMBL27848177 | 0.68 | ABCB11 (0.45) | ALOX5MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10926373 | 0.68 | ABCB11 (0.53) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL512379 | 0.67 | GABRA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204366-A1 | Herbicidal and insecticidal phenyl-substituted pyridazinones | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |