Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | DDO | Q99489 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3786814 | 0.73 | DAO (0.37) | SLC40A1DAODDO | |
| SCHEMBL2748609 | 0.69 | DAO (0.38) | DAODDO | |
| SCHEMBL2749443 | 0.66 | PDE4A (0.43) | SLC40A1MEN1PABPC1KMT2A | |
| SCHEMBL2748946 | 0.66 | PDE4A (0.38) | MEN1PABPC1KMT2A | |
| SCHEMBL23578711 | 0.59 | PDE4A (0.31) | — | |
| SCHEMBL2749205 | 0.59 | PDE4A (0.40) | — | |
| SCHEMBL26386067 | 0.57 | TDO2 (0.40) | MEN1PABPC1KMT2A | |
| SCHEMBL9358268 | 0.54 | CYP3A4 (0.41) | — | |
| SCHEMBL999151 | 0.54 | ALDH1A1 (0.33) | SLC40A1 | |
| SCHEMBL31358029 | 0.53 | METAP2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265270-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009099982-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |