Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781364 | 0.86 | PRSS1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3786562 | 0.84 | PRSS1 (0.32) | — | |
| SCHEMBL3783070 | 0.83 | RXFP1 (0.32) | RXFP1BAZ2B | |
| SCHEMBL3781353 | 0.77 | WDR5 (0.41) | — | |
| SCHEMBL5496944 | 0.77 | NQO2 (0.40) | RXFP1 | |
| SCHEMBL5493324 | 0.76 | NQO2 (0.45) | — | |
| SCHEMBL396796 | 0.74 | TP53 (0.37) | RXFP1 | |
| SCHEMBL5485823 | 0.73 | APP (0.39) | RXFP1BAZ2B | |
| SCHEMBL399316 | 0.71 | NPC1 (0.47) | — | |
| SCHEMBL20090626 | 0.70 | HDAC1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-12-30 | — | — | US | claimed |
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | SELENOI, SCLY, GPX4 | RXFP1 3877/4885BAZ2B 797/4885TGFBR1 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.