Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783282 | 0.83 | WDR5 (0.56) | WDR5PRMT1NQO2ALDH1A1TOP1 | |
| SCHEMBL3505353 | 0.81 | WDR5 (0.54) | WDR5PRMT1NQO2ALDH1A1TOP1 | |
| Hydrochloric Acid SCHEMBL3791148 | 0.81 | WDR5 (0.54) | WDR5PRMT1NQO2ALDH1A1TOP1 | |
| SCHEMBL8975475 | 0.80 | WDR5 (0.53) | WDR5PRMT1UBE2TNQO2ALDH1A1 | |
| SCHEMBL3783070 | 0.79 | RXFP1 (0.32) | — | |
| SCHEMBL8975609 | 0.78 | RXFP1 (0.49) | WDR5PRMT1UBE2TNQO2ALDH1A1 | |
| SCHEMBL3781350 | 0.78 | PRMT1 (0.60) | WDR5PRMT1NQO2ALDH1A1TOP1 | |
| SCHEMBL3786954 | 0.77 | RXFP1 (0.35) | — | |
| SCHEMBL28344110 | 0.77 | P4HA1 (0.52) | WDR5PRMT1UBE2TALDH1A1HPGD | |
| SCHEMBL2013410 | 0.74 | WDR5 (0.54) | WDR5PRMT1NQO2ALDH1A1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-12-30 | — | — | US | claimed |
| WO-2009051796-A2 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-23 | — | — | WO | claimed |
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-12-30 | — | — | US | disclosed |
| WO-2009051796-A2 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331368-A1 | 2,5-DIARYL SELENOPHENE COMPOUNDS, AZA 2,5-DIARYL THIOPHENE COMPOUNDS, AND THEIR PRODRUGS AS ANTIPROTOZOAL AGENTS | SELENOI, SCLY, GPX4 | WDR5 1926/4885PRMT1 788/4885UBE2T 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.