Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780947 | 0.78 | ENPP2 (0.59) | ENPP2KCNH2ORAI1ORAI2ORAI3 | |
| SCHEMBL3790166 | 0.78 | ENPP2 (0.44) | ENPP2KCNH2ORAI1ORAI2ORAI3 | |
| SCHEMBL7777059 | 0.77 | ORAI1 (0.61) | ENPP2KCNH2ORAI1ORAI2ORAI3 | |
| SCHEMBL3790958 | 0.76 | ENPP2 (0.42) | ENPP2KCNH2ORAI1ORAI2ORAI3 | |
| SCHEMBL7227159 | 0.75 | ENPP2 (0.46) | ENPP2ORAI1ORAI2ORAI3KDM4E | |
| SCHEMBL5008996 | 0.75 | ALDH1A1 (0.44) | KCNH2KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL203282 | 0.75 | ENPP2 (0.60) | ENPP2ORAI1ORAI2ORAI3KDM4E | |
| SCHEMBL3820431 | 0.73 | CA1 (0.45) | ENPP2KCNH2ORAI1ORAI2ORAI3 | |
| SCHEMBL29428931 | 0.73 | CA1 (0.45) | ENPP2KCNH2ORAI1ORAI2ORAI3 | |
| Magnesium Chloride Anhydrous SCHEMBL20694977 | 0.72 | ENPP2 (0.52) | ENPP2ORAI1ORAI2ORAI3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ENPP2 1920/4885KCNH2 1145/4885ORAI1 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.