Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693551 | 0.88 | L3MBTL1 (0.39) | PKML3MBTL1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL15204263 | 0.72 | RAB9A (0.37) | RAB9ALMNASMN1; SMN2MAPK10HSD17B10 | |
| SCHEMBL1217220 | 0.71 | KDM4E (0.63) | L3MBTL1RAB9ALMNASMN1; SMN2POLB | |
| SCHEMBL29447914 | 0.71 | KDM4E (0.63) | L3MBTL1RAB9ALMNASMN1; SMN2POLB | |
| SCHEMBL618089 | 0.68 | POLB (0.58) | L3MBTL1RAB9ALMNASMN1; SMN2POLB | |
| SCHEMBL1080763 | 0.67 | KDM4E (0.62) | L3MBTL1SMN1; SMN2TDP1POLBHTT | |
| SCHEMBL29732854 | 0.66 | CAMKK2 (0.46) | MAPK10HSD17B10ALDH1A1KDM4EMAPK1 | |
| SCHEMBL1384475 | 0.66 | CAMKK2 (0.46) | MAPK10HSD17B10ALDH1A1KDM4EMAPK1 | |
| SCHEMBL28098788 | 0.66 | MAP2K1 (0.41) | MAPK10HSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL29623160 | 0.65 | KDM4E (0.47) | L3MBTL1MAPK10HSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123716-A1 | HETEROCYCLIC FUSED CINNOLINE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-10-28 | — | — | WO | disclosed |