Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3788232

CCCc1cccc(Cl)c1.N

nearest known ligand 0.61

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.61
AOC3 Q16853 1/20 0.56
PNMT P11086 2/20 0.54
HTR3E A5X5Y0 3/20 0.52
HTR3B O95264 3/20 0.52
HTR3A P46098 3/20 0.52
HTR3D Q70Z44 3/20 0.52
HTR3C Q8WXA8 3/20 0.52
CHRM2 P08172 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
CYP3A4 P08684 2/20 0.48
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
C3AR1 Q16581 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28484059 0.98 TAAR1 (0.59) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL29848342 0.98 TAAR1 (0.63) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL91272 0.98 TAAR1 (0.63) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL27361590 0.88 CHRM2 (0.57) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL4427360 0.86 TAAR1 (0.52) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL197297 0.85 TAAR1 (0.59) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL12050856 0.84 TAAR1 (0.74) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL14047464 0.83 TAAR1 (0.57) TAAR1AOC3PNMTHTR3EHTR3B
Ammonia Solution, Strong SCHEMBL268556 0.82 PNMT (0.58) TAAR1AOC3PNMTHTR3EHTR3B
SCHEMBL24244205 0.82 LPL (0.57) TAAR1AOC3HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 TAAR1 1746/4885AOC3 63/4885PNMT 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.