SCHEMBL3012871

SCHEMBL3012871

Cc1ccc(NC(=O)O)cc1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.70
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
KMT2A Q03164 2/20 0.62
CYP1A2 P05177 1/20 0.61
FKBP5 Q13451 1/20 0.59
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 2/20 0.58
GAA P10253 2/20 0.58
MAPT P10636 1/20 0.58
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29990241 0.84 POLB (0.68) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL2336203 0.84 POLB (0.68) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL2010056 0.83 POLB (1.00) POLBNPC1RAB9AKMT2AMEN1
SCHEMBL6918008 0.83 POLB (0.66) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL3032296 0.83 POLB (0.66) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL4686246 0.83 HSP90AA1 (0.53) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL30050717 0.83 MAPT (0.55) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL2853227 0.83 ALDH1A1 (0.64) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL378893 0.83 MAPT (0.55) POLBNPC1RAB9AKMT2ACYP1A2
SCHEMBL2886975 0.81 ALDH1A1 (0.56) POLBNPC1RAB9AKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115144498-B Detection of acetylcysteine amino acid and acetylcysteine method for preparing enantiomer content in amino acid granule 浙江金华康恩贝生物制药有限公司 2024-10-29 CN claimed
EP-3630717-B1 A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES COUNCIL SCIENT IND RES (IN) 2022-02-09 EP claimed
US-10703714-B2 Process for the synthesis of aromatic carbamates COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-07-07 US claimed
US-20200148631-A1 A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-05-14 US claimed
EP-3630717-A1 A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES Council of Scientific and Industrial Research (IN) 2020-04-08 EP claimed
WO-2018216036-A1 A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-11-29 WO claimed
EP-1663204-B1 C-KIT MODULATORS AND METHODS OF USE EXELIXIS INC (US) 2014-05-07 EP claimed
US-20080096892-A1 C-Kit Modulators And Methods Of Use EXELIXIS, INC. (US) 2008-04-24 US claimed
CN-118594514-B BINAM-cellulose derivative composite chiral stationary phase and preparation method and application thereof 昆明医科大学 2024-12-10 CN disclosed
CN-115144498-B Detection of acetylcysteine amino acid and acetylcysteine method for preparing enantiomer content in amino acid granule 浙江金华康恩贝生物制药有限公司 2024-10-29 CN disclosed
CN-118594514-A BINAM-cellulose derivative composite chiral stationary phase and preparation method and application thereof 昆明医科大学 2024-09-06 CN disclosed
US-20240083869-A1 ISOINDOLINONE COMPOUNDS MONTE ROSA THERAPEUTICS AG (CH) 2024-03-14 US disclosed
US-11912682-B2 Isoindolinone compounds MONTE ROSA THERAPEUTICS, INC. (US) 2024-02-27 US disclosed
CN-117479838-A Nematicidal composition 石原产业株式会社 2024-01-30 CN disclosed
US-20080096892-A1 C-Kit Modulators And Methods Of Use EXELIXIS, INC. (US) 2008-04-24 US disclosed
EP-1660437-A4 HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF AMOREPACIFIC CORP (KR) 2006-09-20 EP disclosed
EP-1660437-A1 HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF Amorepacific Corporation (KR) 2006-05-31 EP disclosed
WO-2005019162-A1 HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF AMOREPACIFIC CORPORATION (KR) 2005-03-03 WO disclosed
US-4861872-A Alkyl-phenylcarbamate derivative of polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1989-08-29 US disclosed
US-3949023-A PESTICIDE SUMITOMO CHEMICAL CO., LTD. (JA) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096892-A1 C-Kit Modulators And Methods Of Use KIT, PRKCH, PRKCB POLB 3770/4885NPC1 2020/4885RAB9A 1443/4885
US-20240083869-A1 ISOINDOLINONE COMPOUNDS CYP4F2, AOC2, AOC3 POLB 3996/4885NPC1 285/4885RAB9A 3175/4885
US-20200148631-A1 A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES TYR, DDC, ALK POLB 3140/4885NPC1 4157/4885RAB9A 3127/4885
US-10703714-B2 Process for the synthesis of aromatic carbamates ALK, DDC, TYR POLB 2991/4885NPC1 4118/4885RAB9A 3122/4885
US-11912682-B2 Isoindolinone compounds CYP4F2, AOC2, AOC3 POLB 3996/4885NPC1 285/4885RAB9A 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.