SCHEMBL3789090

SCHEMBL3789090

CN(C)c1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.84
CYP3A4 P08684 6/20 0.84
TDP1 Q9NUW8 6/20 0.84
MAPK1 P28482 3/20 0.84
TP53 P04637 2/20 0.84
ALOX15 P16050 2/20 0.84
TSHR P16473 4/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPT P10636 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
CASP3 P42574 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL28276794 1.00 ALDH1A1 (0.84) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL7011532 0.93 ALDH1A1 (0.73) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL15246 0.92 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL8468934 0.92 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL4356329 0.89 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1MAPK1TP53
Hydrochloric Acid SCHEMBL971113 0.89 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1MAPK1TP53
Hydrochloric Acid SCHEMBL309541 0.89 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1MAPK1TP53
Ammonia Solution, Strong SCHEMBL28575167 0.89 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1MAPK1TP53
Water SCHEMBL6142579 0.89 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1MAPK1TP53
Bromide SCHEMBL2353262 0.89 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0166321-B1 HYDROPHOBIC POLYAMIDES BAYER AG (DE) 1990-08-08 EP claimed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
CN-119439625-A Negative photosensitive resin composition, pattern forming method, cured coating film forming method, interlayer insulating film, surface protective film, and electronic component 信越化学工业株式会社 2025-02-14 CN disclosed
CN-118818897-A Radiation-sensitive composition, cured film, method for producing same, semiconductor element, and display element JSR株式会社 2024-10-22 CN disclosed
CN-118795734-A Radiation-sensitive composition, cured film, method for producing cured film, liquid crystal display device, and organic EL display device JSR株式会社 2024-10-18 CN disclosed
CN-118749078-A Photosensitive resin composition set, optical waveguide, method for producing optical waveguide, opto-electric hybrid board, sheet set, core resin composition, coating resin composition, and resin sheet 味之素株式会社 2024-10-08 CN disclosed
CN-117590689-A Radiation-sensitive composition, cured film, method for producing same, display device, and curable resin composition JSR株式会社 2024-02-23 CN disclosed
CN-117148673-A Photosensitive composition and method for producing same, cured product and method for producing same, display element, and polyimide JSR株式会社 2023-12-01 CN disclosed
CN-117148680-A Radiation-sensitive composition, cured film, method for producing cured film, liquid crystal display device, and organic EL display device JSR株式会社 2023-12-01 CN disclosed
CN-116829674-A Liquid repellent, curable composition, cured product, partition wall, organic electroluminescent element, method for producing fluorine-containing coating film, and fluorine-containing coating film 中央硝子株式会社 2023-09-29 CN disclosed
US-20070254889-A1 Compounds and methods useful for rescuing cells from beta-amyloid toxicity and treatment of Alzheimer's disease THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2007-11-01 US disclosed
US-20050271584-A1 Biphenyls and fluorenes as imaging agents in alzheimer's disease THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2005-12-08 US disclosed
EP-1553985-A2 BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE The Trustees of The University of Pennsylvania (US) 2005-07-20 EP disclosed
CN-1638973-A multicolor thermosensitive recording medium JUJO PAPER CO LTD (JP) 2005-07-13 CN disclosed
WO-2004032975-A2 BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2004-04-22 WO disclosed
US-20030134859-A1 PPAR-gamma modulator SANKYO COMPANY, LIMITED (JP) 2003-07-17 US disclosed
EP-1277729-A1 PPAR (GAMMA) MODULATORS Sankyo Company, Limited (JP) 2003-01-22 EP disclosed
EP-0166321-B1 HYDROPHOBIC POLYAMIDES BAYER AG (DE) 1990-08-08 EP disclosed
US-4613631-A Crosslinked polymers for enhanced oil recovery MOBIL OIL CORPORATION (US) 1986-09-23 US disclosed
US-4205988-A Photochromic method involving an aromatic amine ASAHI KASEI K. K. (JP) 1980-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254889-A1 Compounds and methods useful for rescuing cells from beta-amyloid toxicity and treatment of Alzheimer's disease APP, BACE1, IAPP ALDH1A1 1209/4885CYP3A4 946/4885TDP1 245/4885
US-20030134859-A1 PPAR-gamma modulator PPARG, PPARA, PPARD ALDH1A1 583/4885CYP3A4 1516/4885TDP1 4823/4885
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 ALDH1A1 1008/4885CYP3A4 27/4885TDP1 2058/4885
US-20050271584-A1 Biphenyls and fluorenes as imaging agents in alzheimer's disease APP, BACE2, BACE1 ALDH1A1 1533/4885CYP3A4 1143/4885TDP1 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.