Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.48 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.43 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.94 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.94 |
| ▸ | TP53 | P04637 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL309541 | 1.00 | ALDH1A1 (0.94) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL9805647 | 0.97 | ALDH1A1 (0.89) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL8468934 | 0.97 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL15246 | 0.97 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL4356329 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL28575167 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| Bromide SCHEMBL2353262 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| Water SCHEMBL6142579 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| Bromide SCHEMBL20661275 | 0.92 | ALDH1A1 (0.89) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL28273962 | 0.92 | ALDH1A1 (0.89) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119310026-A | Method for detecting content of hydrogen sulfide in acetylcysteine injection | 湖北午时医药研究院有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-115815883-B | Colorless and transparent soldering flux with residues after welding and preparation method thereof | 云南锡业新材料有限公司 | 2024-10-29 | — | — | CN | claimed |
| US-20240166795-A1 | XYLYLENE DIISOCYNATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2024-05-23 | — | — | US | claimed |
| EP-4306509-A1 | XYLYLENE DIISOCYNATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | Wanhua Chemical Group Co., Ltd (CN) | 2024-01-17 | — | — | EP | claimed |
| CN-116940828-A | Method for determining total aldehydes in one or more of crude 2, 5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA), and esters thereof | 阿彻丹尼尔斯米德兰德公司 | 2023-10-24 | — | — | CN | claimed |
| CN-115073707-B | Benzenedimethylene diisocyanate composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116559097-A | Methylene blue spectrophotometry for rapidly determining sulfide | 上海安杰智创科技股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116288732-A | Preparation method of DMPDPbI4 perovskite monocrystal with zirconium ion implantation and application of DMPDPbI4 perovskite monocrystal in photoelectric detector | 西北大学 | 2023-06-23 | — | — | CN | claimed |
| CN-115815883-A | Colorless and transparent flux for postweld residues and preparation method thereof | 云南锡业锡材有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115655837-A | Ammonium salt solution, ferric diamine-Alisine blue staining solution and application thereof | 河南赛诺特生物技术有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-2173033-Y | Medicine for examing and curing gonorrhea | YIN XIN (CN) | 1994-08-03 | — | — | CN | claimed |
| EP-0568777-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1993-11-10 | — | — | EP | claimed |
| US-5085978-A | METHOD FOR PROCESSING LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1992-02-04 | — | — | US | claimed |
| EP-0425258-A1 | Method for processing light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1991-05-02 | — | — | EP | claimed |
| US-4272613-A | DYE DEVELOPER OF A PRIMARY AMINE, DISULFIDE OR DI(MERCAPTAN) AND PYRAZOLIDONE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-06-09 | — | — | US | claimed |
| US-RE30064-E | USE OF COLOR DEVELOPER CONTAINING P-PHENYLENEDIAMINE DEVELOPER AND ORGANIC COMPOUND CONTAINING PHOSPHONO AND CARBOXY GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1979-08-07 | — | — | US | claimed |
| US-4108729-A | Paper booklet for presumptive diagnosis of Neisseria Gonorrhoeae in the male | U.S. PACKAGING CORP. (US) | 1978-08-22 | — | — | US | claimed |
| US-4107284-A | Radioimmunoassay procedure using a stabilized complex | SULTANIAN ISHKHAN V | 1978-08-15 | — | — | US | claimed |
| US-4083723-A | P-PHENYLENEDIAMINE AND DERIVATIVES AND A COMPOUND WITH A CARBOXY AND A PHOSPHONO GROUP AS A COLOR DEVELOPER | FUJI PHOTO FILM CO., LTD. (JA) | 1978-04-11 | — | — | US | claimed |
| US-4018653-A | Instrument for the detection of Neisseria gonorrhoeae without culture | U.S. PACKAGING CORPORATION (US) | 1977-04-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166795-A1 | XYLYLENE DIISOCYNATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | DCXR, NOTUM, FDFT1 | ADRA2A 4814/4885ADRA2B 4554/4885ADRA2C 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.