Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | XDH | P47989 | 3/20 | 0.64 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.64 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.64 |
| ▸ | CA4 | P22748 | 2/20 | 0.64 |
| ▸ | BCL9 | O00512 | 10/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779634 | 0.85 | MEN1 (0.64) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL28013961 | 0.81 | CYP1A2 (0.59) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL30385934 | 0.79 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29390102 | 0.79 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29377152 | 0.79 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL19235 | 0.79 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL3715283 | 0.76 | MEN1 (0.93) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL28182051 | 0.76 | MEN1 (0.93) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL3647372 | 0.76 | CYP1A2 (0.69) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL1144215 | 0.76 | CYP1A2 (0.69) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746006-B1 | METHODS AND DEVICES FOR REDUCING VASCULAR SMOOTH MUSCLE CELL PROLIFERATION | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-06-26 | — | — | EP | disclosed |
| US-12011508-B2 | Methods and devices for reducing vascular smooth muscle cell proliferation | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-06-18 | — | — | US | disclosed |
| US-20210106728-A1 | METHODS AND DEVICES FOR REDUCING VASCULAR SMOOTH MUSCLE CELL PROLIFERATION | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2021-04-15 | — | — | US | disclosed |
| US-20150190253-A1 | COATED DEVICES AND METHODS OF MAKING COATED DEVICES THAT REDUCE SMOOTH MUSCLE CELL PROLIFERATION AND PLATELET ACTIVITY | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2015-07-09 | — | — | US | disclosed |
| US-8992471-B2 | Coated devices and method of making coated devices that reduce smooth muscle cell proliferation and platelet activity | NANOCOPOEIA, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8992603-B2 | Coated devices and method of making coated devices that reduce smooth muscle cell proliferation and platelet activity | NANOCOPOEIA, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130030518-A1 | COATED DEVICES AND METHOD OF MAKING COATED DEVICES THAT REDUCE SMOOTH MUSCLE CELL PROLIFERATION AND PLATELET ACTIVITY | LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER OFFICE OF RESEARCH (US) | 2013-01-31 | — | — | US | disclosed |
| US-20100331965-A1 | COATED DEVICES AND METHOD OF MAKING COATED DEVICES THAT REDUCE SMOOTH MUSCLE CELL PROLIFERATION AND PLATELET ACTIVITY | NANOCOPOEIA, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2009061787-A1 | COATED DEVICES AND METHOD OF MAKING COATED DEVICES THAT REDUCE SMOOTH MUSCLE CELL PROLIFERATION AND PLATELET ACTIVITY | NANOCOPOEIA, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106728-A1 | METHODS AND DEVICES FOR REDUCING VASCULAR SMOOTH MUSCLE CELL PROLIFERATION | VCAM1, MYLK, TNNC1 | CYP1A2 4824/4885MEN1 4691/4885KMT2A 3061/4885 |
| US-12011508-B2 | Methods and devices for reducing vascular smooth muscle cell proliferation | VCAM1, MYLK, TNNC1 | CYP1A2 4824/4885MEN1 4691/4885KMT2A 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.