Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262056 | 0.80 | KMT2A (0.53) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL4705141 | 0.80 | CA12 (0.40) | MEN1KMT2AALDH1A1MAPK8HSD17B10 | |
| SCHEMBL27213297 | 0.79 | KMT2A (0.52) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL16105410 | 0.73 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL2265274 | 0.73 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL20692523 | 0.72 | PDE7A (0.32) | ALOX5 | |
| SCHEMBL13292672 | 0.71 | PRNP (0.36) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12229140 | 0.71 | ALOX5 (0.42) | ALDH1A1MAPTALOX5GAA | |
| SCHEMBL19274403 | 0.69 | — | — | |
| SCHEMBL13155557 | 0.69 | FFAR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188442-A1 | Pyrazole-4-Carboxamide Derivatives as Microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-07 | — | — | US | disclosed |
| EP-1904450-A1 | PYRAZOLE-4- CARBOXAMIDE DERIVATIVES AS MICROBIOCIDES | Syngeta Participations AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007009717-A1 | PYRAZOLE-4- CARBOXAMIDE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188442-A1 | Pyrazole-4-Carboxamide Derivatives as Microbiocides | CD14, FPR1, FPR2 | MEN1 3440/4885KMT2A 3372/4885ALDH1A1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.