Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514895 | 0.82 | ALOX5 (0.50) | KMT2ALMNAALDH1A1CYP2C19HCAR2 | |
| SCHEMBL1283491 | 0.82 | BRD4 (0.50) | ADRB2BRD4FFAR2MEN1KMT2A | |
| SCHEMBL22772305 | 0.82 | ESR1 (0.46) | LMNACYP2C9CYP1A2CYP3A4ADORA3 | |
| SCHEMBL514412 | 0.82 | HCAR2 (0.40) | LMNACYP2C9CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL136981 | 0.82 | FFAR2 (0.49) | ADRB2BRD4FFAR2MEN1KMT2A | |
| SCHEMBL5823639 | 0.81 | ALOX5 (0.51) | MEN1KMT2ACYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL21612915 | 0.81 | ALOX5 (0.51) | MEN1KMT2ACYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL29140774 | 0.81 | ALOX5 (0.51) | MEN1KMT2ACYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL513778 | 0.81 | ACACB (0.40) | LMNACYP2C9TSHRHCAR2 | |
| SCHEMBL28649908 | 0.81 | ALDH1A1 (0.41) | HDAC4HDAC7HDAC5ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1492762-A | Azoles as malonyl-COA decarboxylase inhibitors useful as metabolic modulators | ������ҩ��ʽ���� | 2004-04-28 | — | — | CN | claimed |
| EP-2414420-B1 | CO-CRYSTALLIZABLE DIACETYLENIC MONOMER COMPOSITIONS, CRYSTAL PHASES AND MIXTURES, AND RELATED METHODS | TEMPTIME CORP (US) | 2015-07-08 | — | — | EP | disclosed |
| WO-2010114752-A1 | CO-CRYSTALLIZABLE DIACETYLENIC MONOMER COMPOSITIONS, CRYSTAL PHASES AND MIXTURES, AND RELATED METHODS | TEMPTIME CORPORATION (US) | 2010-10-07 | — | — | WO | disclosed |
| US-5552386-A | COMPOUNDS FOR BACTERICIDES OR ANTIPROTOZOA AGENTS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5314875-A | Method for treating swine dysentery with the derivatives of the antibiotic A82810 | ELI LILLY AND COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0341019-B1 | POLYETHER ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0184291-B1 | POLYETHER ANTIBIOTIC A80190 | ELI LILLY AND COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |
| US-5098834-A | Polyether antibiotics as bactericides and anticoccidial agents | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0341019-A2 | Polyether antibiotic | ELI LILLY AND COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4683201-A | Antibiotic A80190-producing Actinomadura oligospora and process | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| CN-85108210-A | Preparation A80190 antibiotic method | — | 1986-12-03 | — | — | CN | disclosed |
| EP-0184291-A2 | Polyether antibiotic A80190 | ELI LILLY AND COMPANY (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4582822-A | ANIMAL FEED ADDITIVES | ELI LILLY AND COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0036899-B1 | THERMOCHROMIC POLYACETYLENIC COMPOSITION, PROCESS THEREFOR, TEMPERATURE MEASURING AND INDICIA DISPLAYING DEVICES AND PROCESS FOR RECORDING AND THEREAFTER ERASING IMAGES | ALLIED CORPORATION (US) | 1984-08-01 | — | — | EP | disclosed |
| US-4339951-A | Tempeature measurement and display of indicia using thermochromic polyacetylenes | ALLIED CORPORATION (US) | 1982-07-20 | — | — | US | disclosed |
| US-4294925-A | FERMENTATION, AEROBIC PROCESSES | HOFFMANN-LA ROCHE INC. (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0036899-A1 | Thermochromic polyacetylenic composition, process therefor, temperature measuring and indicia displaying devices and process for recording and thereafter erasing images | ALLIED CORPORATION (US) | 1981-10-07 | — | — | EP | disclosed |
| US-4263427-A | REACTING HYDROXYL WITH ISOCYANATE TO OBTAIN ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4242440-A | Thermochromic polyacetylenes used in laser beam recording method | ALLIED CHEMICAL CORPORATION (US) | 1980-12-30 | — | — | US | disclosed |
| US-4215208-A | Thermochromic polyacetylenes containing urethane groups | ALLIED CHEMICAL CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |