Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22772305 | 0.84 | ESR1 (0.46) | LMNAHCAR2CYP2C19TDP1 | |
| SCHEMBL514412 | 0.84 | HCAR2 (0.40) | ALOX5LMNAHCAR2ALDH1A1SCN2A | |
| SCHEMBL28649908 | 0.82 | ALDH1A1 (0.41) | HCAR2ALDH1A1 | |
| SCHEMBL513778 | 0.82 | ACACB (0.40) | ALOX5LMNAHCAR2 | |
| SCHEMBL9090928 | 0.82 | ALDH1A1 (0.41) | HCAR2ALDH1A1 | |
| SCHEMBL5823639 | 0.82 | ALOX5 (0.51) | ALOX5HCAR2ALDH1A1KMT2A | |
| SCHEMBL3789551 | 0.82 | ADRB2 (0.47) | LMNAHCAR2ALDH1A1CYP2C19KMT2A | |
| SCHEMBL21612915 | 0.82 | ALOX5 (0.51) | ALOX5HCAR2ALDH1A1KMT2A | |
| SCHEMBL29140774 | 0.82 | ALOX5 (0.51) | ALOX5HCAR2ALDH1A1KMT2A | |
| SCHEMBL264866 | 0.82 | HCAR2 (0.58) | ALOX5LMNAHCAR2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174297-B | Estrogen receptor modulating compounds | 雷迪厄斯制药公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115722266-B | Azacarbene-amino-ruthenium catalyst, and preparation method and application thereof | 广东药科大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-115722266-A | Novel aza-carbene-amido-ruthenium catalyst and preparation method and application thereof | 广东药科大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-112159401-B | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-06-03 | — | — | CN | disclosed |
| CN-114174297-A | Estrogen receptor modulating compounds | 雷迪厄斯制药公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114040912-A | Compounds for the treatment of kinase-dependent disorders | 埃克塞里艾克西斯公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-112159401-A | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-01-01 | — | — | CN | disclosed |
| WO-2014184071-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| EP-2420493-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-5314875-A | Method for treating swine dysentery with the derivatives of the antibiotic A82810 | ELI LILLY AND COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0341019-B1 | POLYETHER ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0184291-B1 | POLYETHER ANTIBIOTIC A80190 | ELI LILLY AND COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |
| US-5098834-A | Polyether antibiotics as bactericides and anticoccidial agents | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0341019-A2 | Polyether antibiotic | ELI LILLY AND COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4683201-A | Antibiotic A80190-producing Actinomadura oligospora and process | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0184291-A2 | Polyether antibiotic A80190 | ELI LILLY AND COMPANY (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4582822-A | ANIMAL FEED ADDITIVES | ELI LILLY AND COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
| US-4294925-A | FERMENTATION, AEROBIC PROCESSES | HOFFMANN-LA ROCHE INC. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4263427-A | REACTING HYDROXYL WITH ISOCYANATE TO OBTAIN ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1981-04-21 | — | — | US | disclosed |