SCHEMBL3789628

SCHEMBL3789628

Cc1c(N)ccc(-c2cccc(N)c2)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.47
MAP4K4 O95819 6/20 0.44
TSHR P16473 2/20 0.43
CYP3A4 P08684 2/20 0.43
PIK3CA P42336 1/20 0.43
BRD4 O60885 1/20 0.41
RECQL P46063 2/20 0.41
MAOB P27338 1/20 0.41
CASP1 P29466 1/20 0.41
MEN1 O00255 2/20 0.39
PSIP1 O75475 1/20 0.39
AXL P30530 1/20 0.39
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31607625 1.00 MAOA (0.47) MAOAMAP4K4TSHRCYP3A4PIK3CA
SCHEMBL3785555 0.86 MAP4K4 (0.50) MAOAMAP4K4TSHRCYP3A4PIK3CA
SCHEMBL141445 0.79 HSD17B10 (0.50) TSHRCYP3A4PIK3CAKDM4EALDH1A1
SCHEMBL3784883 0.79 POLB (0.57) MAOAMAP4K4TSHRCYP3A4BRD4
SCHEMBL31607643 0.79 POLB (0.57) MAOAMAP4K4TSHRCYP3A4BRD4
SCHEMBL31174707 0.79 POLB (0.57) MAOAMAP4K4TSHRCYP3A4BRD4
SCHEMBL26063261 0.79 FYN (0.51) MAOACYP3A4MAPTALDH1A1
SCHEMBL3785047 0.77 MAP4K4 (0.49) MAOAMAP4K4TSHRCYP3A4PIK3CA
SCHEMBL3789303 0.77 MAOB (0.51) MAOAMAP4K4TSHRCYP3A4BRD4
SCHEMBL3786497 0.77 MAOB (0.51) MAOAMAP4K4TSHRCYP3A4BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947936-B Preparation method of polyetherimide 中节能万润股份有限公司 2023-05-16 CN claimed
CN-115947936-A Preparation method of polyetherimide 中节能万润股份有限公司 2023-04-11 CN claimed
CN-118290690-A Thermoplastic polyurethane for large-caliber extrusion and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN disclosed
CN-117930606-A Intermediate transfer belt, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2024-04-26 CN disclosed
CN-117784556-A Endless belt, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2024-03-29 CN disclosed
CN-117631502-A Transfer device and image forming apparatus 富士胶片商业创新有限公司 2024-03-01 CN disclosed
CN-117590719-A Intermediate transfer belt cleaning system, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2024-02-23 CN disclosed
CN-117518761-A Cleaning blade, image forming apparatus, transfer device, and cleaning apparatus 富士胶片商业创新有限公司 2024-02-06 CN disclosed
CN-116974166-A Inorganic compound particle supply member, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2023-10-31 CN disclosed
CN-116794957-A Endless belt, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2023-09-22 CN disclosed
CN-116774551-A Intermediate transfer belt, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2023-09-19 CN disclosed
CN-111913376-A Belt, intermediate transfer belt, and image forming apparatus 富士施乐株式会社 2020-11-10 CN disclosed
CN-107429028-B Non-aqueous dispersion of fluorine-containing resin, product containing the same, and method for producing the same 三菱铅笔株式会社 2020-06-23 CN disclosed
CN-106019901-B Meandering control member, transfer belt, transfer unit, and image processing apparatus 富士施乐株式会社 2020-04-07 CN disclosed
CN-110955134-A Fixing belt, fixing device, process cartridge, image forming apparatus, and base material for fixing belt 富士施乐株式会社 2020-04-03 CN disclosed
CN-105209936-B Optical element for correcting color blindness 日东电工株式会社 2020-01-14 CN disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
US-7364799-B2 Polyamide-imide resin, flexible metal-clad laminate, and flexible printed wiring board TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-04-29 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
CN-1655075-A Intermediate transfer medium, film forming liquid for the intermediate transfer medium and image forming apparatus using intermediate transfer medium RICOH KK (JP) 2005-08-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 MAOA 348/4885MAP4K4 3704/4885TSHR 1688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.