Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789628 | 0.86 | MAOA (0.47) | MAP4K4CYP3A4TSHRPIK3CAMAOA | |
| SCHEMBL31607625 | 0.86 | MAOA (0.47) | MAP4K4CYP3A4TSHRPIK3CAMAOA | |
| SCHEMBL29636990 | 0.81 | ALDH1A1 (0.62) | MAP4K4CYP3A4MAOABRD4RECQL | |
| SCHEMBL29788122 | 0.81 | ALDH1A1 (0.62) | MAP4K4CYP3A4TSHRPIK3CAMAOA | |
| SCHEMBL30839741 | 0.81 | ALDH1A1 (0.62) | MAP4K4CYP3A4MAOABRD4RECQL | |
| SCHEMBL365320 | 0.81 | ALDH1A1 (0.62) | MAP4K4CYP3A4TSHRPIK3CAMAOA | |
| SCHEMBL2442638 | 0.81 | ALDH1A1 (0.62) | MAP4K4CYP3A4MAOABRD4RECQL | |
| SCHEMBL31607638 | 0.81 | ALDH1A1 (0.62) | MAP4K4CYP3A4MAOABRD4RECQL | |
| SCHEMBL3785934 | 0.81 | TSHR (0.46) | MAP4K4CYP3A4TSHRPIK3CABRD4 | |
| SCHEMBL3785931 | 0.81 | MAOA (0.45) | MAP4K4CYP3A4TSHRMAOABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466251-A | Fused heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-12-13 | — | — | CN | disclosed |
| CN-113603663-A | Method for preparing biphenyl dianhydride isomer through ultrasonic-assisted catalytic coupling | 哈尔滨工业大学（威海） | 2021-11-05 | — | — | CN | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MAP4K4 3704/4885CYP3A4 177/4885TSHR 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.