Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789911 | 0.92 | ABCB1 (0.36) | NOTUMABCB1HTR2C | |
| SCHEMBL3790557 | 0.92 | ABCB1 (0.33) | NOTUMABCB1HTR2CCHRNB2CHRNA4 | |
| SCHEMBL30002535 | 0.91 | ABCB1 (0.39) | NOTUMABCB1 | |
| SCHEMBL3789806 | 0.91 | ABCB1 (0.39) | NOTUMABCB1 | |
| SCHEMBL4345990 | 0.89 | CHRNB2 (0.39) | NOTUMABCB1CHRNB2CHRNA4ENPP2 | |
| SCHEMBL3787278 | 0.82 | ABCB1 (0.32) | NOTUMABCB1PDK2CHRNB2CHRNA4 | |
| SCHEMBL29469211 | 0.81 | ENPP2 (0.40) | NOTUMHTR2CENPP2DRD2SLC6A4 | |
| SCHEMBL3784784 | 0.81 | ENPP2 (0.40) | NOTUMHTR2CENPP2DRD2SLC6A4 | |
| SCHEMBL3786616 | 0.78 | NOTUM (0.37) | NOTUMHTR2CPDK2PDK4PDK1 | |
| SCHEMBL23043664 | 0.78 | SMN1; SMN2 (0.40) | NOTUMHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | NOTUM 36/4885ABCB1 826/4885HTR2C 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.