Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.39 |
| ▸ | S100A10 | P60903 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780720 | 0.89 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAOAMAOBBCL2 | |
| SCHEMBL3790322 | 0.85 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAOAMAOBBCL2 | |
| SCHEMBL3784772 | 0.80 | CYP3A4 (0.48) | ALDH1A1MAOAMAOBBCL2MCL1 | |
| SCHEMBL3791339 | 0.80 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAOAMAOBBCL2 | |
| SCHEMBL30398364 | 0.79 | MAOA (0.47) | ALDH1A1MAOAMAOBBCL2MCL1 | |
| SCHEMBL6366825 | 0.79 | MAOA (0.47) | ALDH1A1MAOAMAOBBCL2MCL1 | |
| SCHEMBL3789395 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAOAMAOBBCL2 | |
| SCHEMBL2425694 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAOBHSD17B10ADORA2A | |
| Diphenylsulfane SCHEMBL19712994 | 0.78 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1MAOAMAOBHSD17B10 | |
| SCHEMBL3790938 | 0.78 | MAOA (0.48) | ALDH1A1MAOAMAOBBCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885L3MBTL1 3838/4885MAOA 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.