Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.92 |
| ▸ | PTPRC | P08575 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL30585392 | 1.00 | PTPN1 (0.92) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| SCHEMBL423603 | 0.96 | PTPN1 (1.00) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| SCHEMBL29355012 | 0.96 | PTPN1 (1.00) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9233999 | 0.96 | PTPN1 (0.92) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| Potassium Ion SCHEMBL1520490 | 0.84 | PTPN1 (0.67) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| Potassium Ion SCHEMBL29359597 | 0.84 | PTPN1 (0.67) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| SCHEMBL30708248 | 0.80 | PTPN1 (0.72) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| Lithium Ion SCHEMBL7788948 | 0.80 | PTPN1 (0.67) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9237165 | 0.80 | PTPN1 (0.67) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 | |
| SCHEMBL465089 | 0.80 | PTPN1 (0.72) | PTPN1PTPRCKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504866-B | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2023-09-26 | — | — | CN | claimed |
| EP-2444500-B1 | Measurement method using oxidase | ARKRAY INC (JP) | 2016-06-29 | — | — | EP | claimed |
| US-8722355-B2 | Measurement method using oxidase | ARKRAY, INC. (JP) | 2014-05-13 | — | — | US | claimed |
| EP-1679508-B1 | BIOSENSOR AND METHOD FOR PREPARATION THEREOF | ARKRAY INC (JP) | 2010-07-21 | — | — | EP | claimed |
| US-20070034512-A1 | Biosensor and method for producing the same | ARKRAY, INC. (JP) | 2007-02-15 | — | — | US | claimed |
| EP-1679508-A1 | BIOSENSOR AND METHOD FOR PREPARATION THEREOF | Arkray, Inc. (JP) | 2006-07-12 | — | — | EP | claimed |
| CN-1782701-A | Quick detecting method for aspartate amino transferase vitality | INST ELECTRONICS CAS (CN) | 2006-06-07 | — | — | CN | claimed |
| US-5171689-A | Solid state bio-sensor | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-12-15 | — | — | US | claimed |
| US-4897173-A | Biosensor and method for making the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-01-30 | — | — | US | claimed |
| EP-0136362-A1 | BIOSENSOR | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1985-04-10 | — | — | EP | claimed |
| JP-4113262-A | — | — | None | — | — | JP | disclosed |
| JP-9316022-A | — | — | None | — | — | JP | disclosed |
| CN-115504866-B | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| EP-3130916-B1 | MEASURING METHOD OF A SENSOR USING AN INTERDIGITATED ARRAY ELECTRODE, MEASURING APPARATUS AND MEASURING PROGRAM | ARKRAY INC (JP) | 2022-01-12 | — | — | EP | disclosed |
| EP-2803992-B1 | Sample analyzing method by capillary electrophoresis method | ARKRAY INC (JP) | 2021-02-17 | — | — | EP | disclosed |
| JP-H04113262-A | BIOSENSOR AND MANUFACTURE THEREOF | MATSUSHITA ELECTRIC IND CO LTD | 1992-04-14 | — | — | JP | disclosed |
| EP-0237108-B1 | PROCESS FOR THE PREPARATION OF CARBONYL COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-26 | — | — | EP | disclosed |
| US-4897173-A | Biosensor and method for making the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0230472-A1 | BIOSENSOR AND METHOD OF MANUFACTURING SAME | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0136362-A1 | BIOSENSOR | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |