SCHEMBL3792161

SCHEMBL3792161

COc1ccc(-c2nc(-c3cccc4ccccc34)oc2-c2ccc(OC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.48
ALDH1A1 P00352 9/20 0.48
MAPT P10636 9/20 0.48
GAA P10253 5/20 0.48
GLA P06280 4/20 0.48
HPGD P15428 4/20 0.48
HSD17B10 Q99714 3/20 0.48
CASP1 P29466 2/20 0.48
CASP7 P55210 2/20 0.48
LMNA P02545 2/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ATM Q13315 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
CYP2C19 P33261 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
GPR55 Q9Y2T6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5847041 0.84 KDM4E (0.64) KDM4EALDH1A1MAPTGAAHPGD
SCHEMBL3792164 0.80 ALDH1A1 (0.58) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL29421028 0.80 KDM4E (0.46) KDM4EALDH1A1MAPTGAAHPGD
SCHEMBL1890032 0.76 PPARG (0.56) RAB9ACYP1A2CYP3A4CYP2C19FLT3
SCHEMBL15365218 0.73 ALDH1A1 (0.62) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL7808315 0.73 USP1 (0.71) KDM4EALDH1A1MAPTHPGDLMNA
SCHEMBL8219599 0.73 FLT3 (0.49) KDM4EALDH1A1MAPTHPGDLMNA
SCHEMBL29580516 0.72 ALDH1A1 (0.49) KDM4EALDH1A1MAPTGAAGLA
SCHEMBL29154641 0.72 MAPK13 (0.65) KDM4EALDH1A1MAPTHPGDLMNA
SCHEMBL9613076 0.71 ENPP1 (0.48) KDM4EALDH1A1MAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7376169-B2 Optical phase conjugation laser diode HENRICHS JOSEPH REID 2008-05-20 US claimed
US-20020024297-A1 Multiple layer organic thin films HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) 2002-02-28 US claimed
US-5674636-A Article comprising a microcavity light source AGERE SYSTEMS LLC 1997-10-07 US claimed
US-20100279446-A1 OPTICAL PHASE CONJUGATION LASER DIODE HENRICHS JOSEPH REID 2010-11-04 US disclosed
US-7738522-B2 Optical phase conjugation laser diode HENRICHS JOSEPH REID 2010-06-15 US disclosed
US-20080205461-A1 Optical phase conjugation laser diode HENRICHS JOSEPH R 2008-08-28 US disclosed
US-7376169-B2 Optical phase conjugation laser diode HENRICHS JOSEPH REID 2008-05-20 US disclosed
US-20060198404-A1 Optical phase conjugation laser diode HENRICHS JOSEPH R 2006-09-07 US disclosed
EP-0786925-B1 White light-emitting electroluminescent devices EASTMAN KODAK CO (US) 2002-06-19 EP disclosed
US-20020024297-A1 Multiple layer organic thin films HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) 2002-02-28 US disclosed
US-5881089-A Article comprising an organic laser LUCENT TECHNOLOGIES INC. (US) 1999-03-09 US disclosed
US-5674636-A Article comprising a microcavity light source AGERE SYSTEMS LLC 1997-10-07 US disclosed