Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545274 | 0.83 | MEN1 (0.55) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL27761235 | 0.74 | SLC2A1 (0.63) | PDK1MEN1KMT2AHTTMAPT | |
| SCHEMBL27783022 | 0.73 | PDK1 (0.63) | PDK1MEN1KMT2AHTTMAPT | |
| SCHEMBL27783025 | 0.72 | MAPT (0.65) | PDK1MEN1KMT2AHTTMAPT | |
| SCHEMBL7754222 | 0.72 | PDK1 (0.58) | PDK1MEN1KMT2AHTTMAPT | |
| SCHEMBL27783031 | 0.71 | ALDH1A1 (0.61) | PDK1MEN1KMT2AHTTMAPT | |
| SCHEMBL28780158 | 0.71 | PDK1 (0.56) | PDK1MEN1KMT2AHTTMAPT | |
| SCHEMBL11420060 | 0.71 | HSD17B10 (0.43) | PDK1HSD11B1MEN1KMT2A | |
| SCHEMBL2787734 | 0.70 | NR1H4 (0.47) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL15544997 | 0.70 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101570494-B | N-phenyl-dichloroacetamide and derivatives as well as preparation method and application thereof | UNIV TSINGHUA | 2013-04-03 | — | — | CN | disclosed |
| WO-2010139090-A1 | N-PHENYL DICHLOROACETAMIDE AND THEIR DERIVATIVES, PREPARATION METHODS AND USES THEIROF | 清华大学 (CN) | 2010-12-09 | — | — | WO | disclosed |
| CN-101570494-A | N-phenyl-dichloroacetamide and derivatives as well as preparation method and application thereof | UNIV TSINGHUA (CN) | 2009-11-04 | — | — | CN | disclosed |