Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.55 |
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666582 | 0.89 | PDK1 (0.67) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL30525296 | 0.87 | CETP (0.59) | CETPLMNAPOLBMEN1KMT2A | |
| SCHEMBL15621420 | 0.84 | PDK1 (0.69) | PDK1PDK2PDK3PDK4CETP | |
| SCHEMBL29524443 | 0.84 | PDK1 (0.68) | PDK1PDK2PDK3PDK4CETP | |
| SCHEMBL3535796 | 0.84 | PDK1 (0.68) | PDK1PDK2PDK3PDK4CETP | |
| SCHEMBL14866056 | 0.83 | PDK1 (0.70) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL2432475 | 0.83 | LMNA (0.72) | CETPLMNAPOLBKMT2AHTT | |
| SCHEMBL3785961 | 0.82 | CETP (0.58) | PDK1PDK2PDK3PDK4CETP | |
| SCHEMBL17855986 | 0.81 | PDK1 (0.58) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL30447460 | 0.81 | PDK1 (0.58) | PDK1PDK2PDK3PDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | PDK1 2822/4885PDK2 1089/4885PDK3 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.