Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 18/20 | 0.34 |
| ▸ | DRD2 | P14416 | 17/20 | 0.34 |
| ▸ | DRD3 | P35462 | 17/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9789947 | 0.90 | ACHE (0.35) | DRD1HTR2AHTR2CHTR2B | |
| SCHEMBL3798049 | 0.82 | EED (0.37) | DRD1HTR2ADRD2DRD3 | |
| SCHEMBL123730 | 0.76 | HTR2A (0.36) | DRD1HTR2ADRD2DRD3HTR2C | |
| SCHEMBL13711560 | 0.76 | DRD1 (0.37) | DRD1HTR2ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9263909 | 0.75 | ADRA2A (0.34) | — | |
| SCHEMBL126247 | 0.73 | DRD2 (0.37) | HTR2ADRD2DRD3 | |
| SCHEMBL9789848 | 0.72 | CTNNB1 (0.35) | DRD1HTR2AHTR2CHTR2B | |
| SCHEMBL24529108 | 0.72 | NOS3 (0.46) | DRD1HTR2ADRD2DRD3HTR2C | |
| SCHEMBL31299097 | 0.72 | DRD1 (0.37) | DRD1HTR2ADRD2DRD3 | |
| SCHEMBL17190972 | 0.72 | DRD1 (0.46) | DRD1HTR2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |