Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24126892 | 0.82 | L3MBTL1 (0.36) | ALDH1A1 | |
| SCHEMBL20792487 | 0.79 | TYMS (0.43) | DYRK1ATYMS | |
| SCHEMBL12820951 | 0.78 | DYRK1A (0.46) | DYRK1ATYMS | |
| SCHEMBL18520454 | 0.76 | DYRK1A (0.47) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL21161374 | 0.75 | TYMS (0.49) | TYMS | |
| SCHEMBL12884842 | 0.75 | TYMS (0.46) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL24704369 | 0.75 | DYRK1A (0.46) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL15061831 | 0.75 | TYMS (0.48) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL3391755 | 0.74 | DYRK1A (0.42) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL25899172 | 0.74 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |