Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12884842 | 0.80 | TYMS (0.46) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL12820951 | 0.80 | DYRK1A (0.46) | DYRK1ATYMS | |
| SCHEMBL15061831 | 0.80 | TYMS (0.48) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL24704369 | 0.80 | DYRK1A (0.46) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL21161374 | 0.77 | TYMS (0.49) | TYMS | |
| SCHEMBL166747 | 0.77 | TYMS (0.49) | TYMS | |
| SCHEMBL94358 | 0.76 | CHUK (0.56) | TYMS | |
| SCHEMBL3391755 | 0.76 | DYRK1A (0.42) | DYRK1ATYMSMAPTKDM4EALDH1A1 | |
| SCHEMBL22227944 | 0.76 | TYMS (0.50) | DYRK1ATYMS | |
| SCHEMBL3793648 | 0.76 | DYRK1A (0.42) | DYRK1ATYMSMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-B1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020057546-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | 上海迪诺医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |
| WO-2017027646-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | WO | disclosed |