Known targets — ChEMBL curated mechanism
SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL379368 | 0.85 | CPT2 (0.44) | TSHRALDH1A1LMNAAPEX1CPT2 | |
| Aspartic Acid SCHEMBL1302396 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL1301554 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL1301523 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL7703371 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL9293073 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL1259586 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL1302394 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL1302714 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL1301891 | 0.80 | GRIK1 (0.50) | SLC7A5GRIK1GRIK2GRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059904-A1 | SUPRAMOLECULAR ASSEMBLIES AND COMPOSITIONS COMPRISING THE SAME | ELC MANAGEMENT LLC (US) | 2025-03-27 | — | — | WO | claimed |
| US-20250332081-A1 | A Composition Against Osmotic Stress | ELC MAN LLC (US) | 2025-10-30 | — | — | US | disclosed |
| WO-2025059904-A1 | SUPRAMOLECULAR ASSEMBLIES AND COMPOSITIONS COMPRISING THE SAME | ELC MANAGEMENT LLC (US) | 2025-03-27 | — | — | WO | disclosed |
| EP-4469023-A1 | A COMPOSITION AGAINST OSMOTIC STRESS | ELC Management LLC (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023141799-A1 | A COMPOSITION AGAINST OSMOTIC STRESS | ELC MANAGEMENT LLC (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20160287658-A1 | COMPOSITION FOR MOISTURIZING SKIN | AMOREPACIFIC CORPORATION (KR) | 2016-10-06 | — | — | US | disclosed |
| EP-2408315-B1 | A METHOD OF REDUCING THE RATE OF DEGRADATION OF A BIOLOGICAL MATERIAL | BIO ENERGY INGREDIENTS LTD (GB) | 2014-12-10 | — | — | EP | disclosed |
| EP-2633762-A1 | A method of reducing the rate of degradation of a biological material | Bio-Energy Ingredients Limited (GB) | 2013-09-04 | — | — | EP | disclosed |
| CN-102524703-A | Betaine natural vegetable and fruit powder and preparation method thereof | BEIJING FUYOU LONGHUI BIO TECHNOLOGY CO LTD | 2012-07-04 | — | — | CN | disclosed |
| EP-2408315-A2 | A METHOD OF REDUCING THE RATE OF DEGRADATION OF A BIOLOGICAL MATERIAL | Bio-Energy Ingredients Limited (GB) | 2012-01-25 | — | — | EP | disclosed |
| US-20120009280-A1 | METHOD OF REDUCING THE RATE OF DEGRADATION OF A BIOLOGICAL MATERIAL | BIO-ENERGY INGREDIENTS LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
| WO-2010106475-A2 | A METHOD OF REDUCING THE RATE OF DEGRADATION OF A BIOLOGICAL MATERIAL | BIO-ENERGY INGREDIENTS LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
| US-6354965-B1 | Golf balls including low water activity fluid and methods for making same | ACUSHNET COMPANY | 2002-03-12 | — | — | US | disclosed |
| US-4703045-A | BETAINE SALTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1987-10-27 | — | — | US | disclosed |
| US-4593020-A | Betaine citrate | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1986-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250332081-A1 | A Composition Against Osmotic Stress | CUTA, SLC6A12, LBR | TSHR 3037/4885ALDH1A1 3858/4885LMNA 962/4885 |
| US-20120009280-A1 | METHOD OF REDUCING THE RATE OF DEGRADATION OF A BIOLOGICAL MATERIAL | PIGS, CD68, GYS1 | TSHR 3180/4885ALDH1A1 4608/4885LMNA 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.