Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214913 | 0.62 | NOS2 (0.51) | NISCH | |
| SCHEMBL15276735 | 0.59 | MEN1 (0.50) | DAOKDM4EPTPN2 | |
| SCHEMBL27604301 | 0.57 | KDM4E (0.44) | KDM4E | |
| SCHEMBL30002428 | 0.57 | GPR35 (0.30) | KDM4E | |
| SCHEMBL16011935 | 0.56 | KDM4E (0.46) | KDM4EPTPN2 | |
| SCHEMBL20783711 | 0.54 | KDM4E (0.57) | KDM4EPTPN2 | |
| SCHEMBL3316024 | 0.53 | KMT2A (0.50) | KDM4EPTPN2 | |
| SCHEMBL28256987 | 0.53 | PTPN2 (0.44) | KDM4EPTPN2PTPN1 | |
| SCHEMBL69159 | 0.53 | ALDH1A1 (0.58) | KDM4EPTPN2PTPN1 | |
| SCHEMBL121301 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004900-A1 | THIENOPYRIMIDINE COMPOUNDS | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | WO | disclosed |