Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL379591

C=C(CCCC[Si](OC)(OC)OC)C(=O)O.S

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.37
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111603 0.98 TBXAS1 (0.38) TBXAS1LMNAALDH1A1
SCHEMBL6917515 0.96 TBXAS1 (0.41) TBXAS1LMNAALDH1A1
SCHEMBL6900214 0.96 TBXAS1 (0.37) TBXAS1LMNAALDH1A1
SCHEMBL6914962 0.96 TBXAS1 (0.41) TBXAS1LMNAALDH1A1
SCHEMBL6909603 0.96 TBXAS1 (0.41) TBXAS1LMNAALDH1A1
Methacrylic Acid SCHEMBL8054976 0.93 TBXAS1 (0.36) TBXAS1
SCHEMBL691967 0.92 TBXAS1 (0.36) TBXAS1LMNA
SCHEMBL8414115 0.91 TBXAS1 (0.35) TBXAS1LMNA
Hydrogen Sulfide SCHEMBL5081973 0.91 TBXAS1 (0.33) TBXAS1LMNA
SCHEMBL6915554 0.86 TBXAS1 (0.34) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 898 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188250-A1 FUNCTIONALIZED SILICA, MASTERBATCH COMPRISING THE SAME, AND RUBBER ARTICLES COMPRISING THE SAME THE GOODYEAR TIRE & RUBBER COMPANY 2025-06-12 US claimed
CN-120118396-A Functionalized silica, masterbatch comprising same, and rubber article comprising same 固特异轮胎和橡胶公司 2025-06-10 CN claimed
CN-110199187-B Method for predicting rubber reinforcing effect of organic-inorganic composite material for rubber reinforcement 株式会社LG化学 2022-02-11 CN claimed
CN-110191917-B Organic-inorganic composite material for rubber reinforcement, method for preparing the same, and rubber composition for tire comprising the same 株式会社LG化学 2021-05-25 CN claimed
CN-107108908-B Method for producing rubber composition for tire, and tire 住友橡胶工业株式会社 2020-05-15 CN claimed
US-20040014869-A1 Method for preparing silica filled elastomeric compositions WONG WAI KEUNG (BE) 2004-01-22 US claimed
EP-1309657-A2 METHOD FOR PREPARING SILICA FILLED ELASTOMERIC COMPOSITIONS Exxonmobil Chemical Patents Inc. (US) 2003-05-14 EP claimed
WO-2001096463-A2 METHOD FOR PREPARING SILICA FILLED ELASTOMERIC COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-12-20 WO claimed
EP-0663421-B1 Tyre tread prepared with a rubber composition UNIROYAL ENGLEBERT GMBH (DE) 1999-04-28 EP claimed
EP-0708137-B1 Vulcanizable rubber composition and tire prepared therefrom UNIROYAL ENGLEBERT GMBH (DE) 1999-03-31 EP claimed
EP-0708136-B1 Rubber blend and tread base prepared therefrom UNIROYAL ENGLEBERT GMBH (DE) 1999-03-03 EP claimed
EP-4438340-B1 TIRE WITH IMPROVED RUBBER COMPOUND BRIDGESTONE EUROPE NV SA (BE) 2026-05-27 EP disclosed
US-12630696-B2 Rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-05-19 US disclosed
US-20260055262-A1 RUBBER COMPOSITION FOR TIRES YOKOHAMA RUBBER CO LTD (JP) 2026-02-26 US disclosed
EP-4349614-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-02-25 EP disclosed
EP-0869145-A1 Rubber composition improved in anti-static property and pneumatic tire using the same Bridgestone Corporation (JP) 1998-10-07 EP disclosed
US-5804636-A ADDING SILANE-BASED COUPLING AGENT PIRELLI COORDINAMENTO PNEUMATICI S.P.A. (IT) 1998-09-08 US disclosed
EP-0767179-A2 Method for producing a rubber composition Bridgestone Corporation (JP) 1997-04-09 EP disclosed
EP-0728803-A1 Process for producing a vulcanizable rubber composition with silica-based reinforcing filler PIRELLI COORDINAMENTO PNEUMATICI S.p.A. (IT) 1996-08-28 EP disclosed
EP-0697432-A1 Rubber composition for tire treads BRIDGESTONE CORPORATION (JP) 1996-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055262-A1 RUBBER COMPOSITION FOR TIRES TRRAP, RAD51, TERT TBXAS1 194/4885LMNA 745/4885ALDH1A1 2033/4885
US-12630696-B2 Rubber composition, and tire THRB, RIF1, THRA TBXAS1 806/4885LMNA 939/4885ALDH1A1 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.