Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 4/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757092 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL30862079 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL5594805 | 0.78 | CYP1A2 (0.43) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL7757773 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL29951357 | 0.76 | ERN1 (0.55) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL28669144 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL3409591 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL29952946 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL8057946 | 0.72 | LMNA (0.42) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL9760066 | 0.72 | PIM1 (0.39) | ALDH1A1MEN1KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121585-B1 | NOVEL AMINOGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | ANAMAR AB (SE) | 2014-05-28 | — | — | EP | disclosed |
| US-8372878-B2 | Aminoguanidines as melanocortin receptor ligands | ANAMAR AB (SE) | 2013-02-12 | — | — | US | disclosed |
| US-20100056641-A1 | Novel Aminoguanidines as Melanocortin Receptor Ligands | ACURE PHARMA AB (SE) | 2010-03-04 | — | — | US | disclosed |
| EP-2121585-A1 | NOVEL AMINOGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS. | Acure Pharma AB (SE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008071980-A1 | NOVEL AMINOGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS. | ACURE PHARMA AB (SE) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056641-A1 | Novel Aminoguanidines as Melanocortin Receptor Ligands | MC1R, MC3R, MC4R | ALDH1A1 2475/4885MEN1 1535/4885KMT2A 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.